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| Name | Class |
|---|---|
| Kyunghee University Medical Center | OTHER |
| Inha University Hospital | OTHER |
| Ewha Womans University | OTHER |
| Hanyang University |
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The purpose of this study is to assess therapeutic confirmation of AG NPP709 syrup to evaluate the safety and efficacy in patients with acute upper respiratory tract infection and chronic inflammatory bronchitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AG NPP709 syrup | Experimental | AG NPP709 contains Ivy leaf extract and coptis rhizoma extract |
|
| Ivy leaf extract syrup | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| AG NPP709syrup | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| improvement by global assessment | At closing visit, researcher assess clinical efficacy using the following five criteria (4: cure, 3: significant improvement, 2: improvement, 1: some improvement, 0: non-improvement or worsening of symptoms). Upper the Grade 3 outcomes are defined as "clinical success". | 5 days |
| Measure | Description | Time Frame |
|---|---|---|
| determine safety by unwanted reaction, clinical laboratory test and physical examination | 5 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Young-ho Na, PhD, MD | Kyung Hee University Medical Center, Department of Pediatrics, | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Inha University Hospital, Department of Pediatrics | Incheon | South Korea | ||||
| Ewha Womens University Medical Center Mokdong Hospital, Department of Allergology |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41807028 | Derived | Cho YJ, Yoon HJ, Lim DH, Yoo KH, Choi SH, Rha YH. Randomized, Double-Blind, Multicenter, Phase 3 Study of AG NPP709 Compared With Ivy Leaf Extract in Patients With Acute or Chronic Respiratory Symptoms. J Korean Med Sci. 2026 Mar 9;41(9):e97. doi: 10.3346/jkms.2026.41.e97. |
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| OTHER |
| Konkuk University Medical Center | OTHER |
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| Seoul |
| South Korea |
| Hanyang University Medical Center, Department of Respiratory Medicine | Seoul | South Korea |
| Konkuk University Medical Center, Department of Respiratory Medicine | Seoul | South Korea |
| Kyung Hee University International Medical Service, Department of Pediatrics | Seoul | South Korea |
| Kyung Hee University Medical Center, Department of Pediatrics, | Seoul | South Korea |
| ID | Term |
|---|---|
| D001991 | Bronchitis |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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