Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure

Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure

The purpose of this study is to determine if choline bitartrate can be administered daily to children with prenatal alcohol exposure, ages 2.5 to 5, as a potential treatment for brain development and cognitive functioning.

Inclusion Criteria:

• Available parent or legal guardian capable of participating in informed consent process
• Documented history of heavy prenatal alcohol exposure (self-report, social service records, or adoption records) or presence of facial dysmorphology characteristic of FASD or both
• Evidence of cognitive deficit in at least one neurocognitive domain

Exclusion Criteria:

• History of neurological condition (ex. epilepsy, cerebral palsy, traumatic brain injury)
• History of medical condition known to affect brain function
• History of other neurodevelopmental disorder (ex. autism, down syndrome)
• History of very low birthweight (<1500 grams)
• History of prenatal exposure to drugs other than alcohol, nicotine, and caffeine