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| Name | Class |
|---|---|
| Seoul National University Hospital | OTHER |
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The purpose of this study is to compare and evaluate the pharmacokinetic characteristics and the safety of fimasartan in renal impairment patients and healthy volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| renal impairment patients | Experimental | renal impairment patients who eGFR is lower than 30 ml/min/1.73m^2 without hemodialysis |
|
| healthy volunteers | Active Comparator | healthy volunteers group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fimasartan | Drug | single administration of fimasartan 120mg |
|
| Measure | Description | Time Frame |
|---|---|---|
| pharmacokinetic characteristic of fimasartan | AUC, Cmax, Tmax, T1/2, and CL/F of fimasartan | 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, 12, 24, 32, 48h |
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Inclusion Criteria:
<Renal impairment patient>
<Healthy volunteer>
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yon Su Kim, PhD | Seoul National University College of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | South Korea |
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| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| C558933 | fimasartan |
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