A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Renal Impairment Patients and Healthy Volunteers

A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Renal Impairment Patients and Healthy Volunteers

The purpose of this study is to compare and evaluate the pharmacokinetic characteristics and the safety of fimasartan in renal impairment patients and healthy volunteers.

Inclusion Criteria:

<Renal impairment patient>

• age: 20-65 years
• eGFR: < 30ml/min/1.73m^2
• not on dialysis
• body weight: greater than 55kg
• written informed consent

<Healthy volunteer>

• age: 20-65 years
• body weight: greater than 55kg
• written informed consent

Exclusion Criteria:

• AST, ALT > 1.5 times of upper normal range
• positive drug or alcohol screening