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Study funding period reached conclusion. Sample size sufficient to complete the analysis on benzodiazepines.
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| Name | Class |
|---|---|
| Canadian Institutes of Health Research (CIHR) | OTHER_GOV |
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An educational intervention targeting community-dwelling older adults will lead to a reduction in potentially inappropriate prescriptions (e.g. benzodiazepines, oxybutynin).
Cessation of potentially inappropriate medications (e.g. benzodiazepines, oxybutynin)will lead to improved cognitive outcomes in older adults.
This study tests the effectiveness of a knowledge transfer tool for empowering patients to engage in collaborative discontinuation of potentially inappropriate medication with their pharmacist and/or physician
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Educational intervention | Experimental | Administration of an educational intervention to inform patients of the risks and safe alternatives to their current potentially inappropriate medication. The textual content of this knowledge transfer tool will be divided into three parts: a) presentation of the evidence-based risks associated with the targeted potentially inappropriate medication (e.g. benzodiazepines); b) presentation of evidence-based equally or more effective therapeutic substitutes for the medical condition (e.g. insomnia and anxiety); and c) presentation of evidence based tapering recommendations where applicable. |
|
| Wait-list group | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| knowledge transfer tool | Behavioral | knowledge transfer tool for empowering patients to engage in collaborative discontinuation of potentially inappropriate medication with their pharmacist and/or physician |
| Measure | Description | Time Frame |
|---|---|---|
| Complete discontinuation of the targeted potentially inappropriate medication (e.g. benzodiazepines, oxybutynin) | 6 months post-intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive function | Montreal cognitive assessment instrument Rey's auditory verbal learning test (immediate memory, learning, and delayed recall) | 6-months post-intervention |
| Sleep efficiency | Sleep efficiency as documented with a sleep diary |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Cara Tannenbaum, MD | Centre de recherche de l'Institut universitaire de gériatrie de Montréal | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Le Groupe Jean Coutu Inc. | Longueuil | Quebec | J4G 1S8 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28473524 | Derived | Martin P, Tannenbaum C. A realist evaluation of patients' decisions to deprescribe in the EMPOWER trial. BMJ Open. 2017 May 4;7(4):e015959. doi: 10.1136/bmjopen-2017-015959. | |
| 28143413 | Derived | Martin P, Tannenbaum C. Use of the EMPOWER brochure to deprescribe sedative-hypnotic drugs in older adults with mild cognitive impairment. BMC Geriatr. 2017 Jan 31;17(1):37. doi: 10.1186/s12877-017-0432-5. |
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| 6-months |
| incontinence-related self-efficacy | incontinence-related self-efficacy as measured with the geriatric self-efficacy index | 6-months post-intervention |
| frequency of urinary incontinence episodes | frequency of urinary incontinence as measured with a 72-hour bladder diary | 6-months post-intervention |
| 24733354 | Derived | Tannenbaum C, Martin P, Tamblyn R, Benedetti A, Ahmed S. Reduction of inappropriate benzodiazepine prescriptions among older adults through direct patient education: the EMPOWER cluster randomized trial. JAMA Intern Med. 2014 Jun;174(6):890-8. doi: 10.1001/jamainternmed.2014.949. |
| 23514019 | Derived | Martin P, Tamblyn R, Ahmed S, Tannenbaum C. An educational intervention to reduce the use of potentially inappropriate medications among older adults (EMPOWER study): protocol for a cluster randomized trial. Trials. 2013 Mar 20;14:80. doi: 10.1186/1745-6215-14-80. |
| ID | Term |
|---|---|
| D007319 | Sleep Initiation and Maintenance Disorders |
| D001008 | Anxiety Disorders |
| ID | Term |
|---|---|
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
| D001523 | Mental Disorders |
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