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| ID | Type | Description | Link |
|---|---|---|---|
| 5R01MH084935 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| University of Pittsburgh | OTHER |
| Kaiser Permanente | OTHER |
| National Institute of Mental Health (NIMH) | NIH |
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The purpose of this study is to determine whether a brief (12 week) psychological treatment program, based in primary care, can help youths struggling with anxiety and/or depression. This brief cognitive behavioral therapy program will be compared to enhanced referral to specialty mental health care.
Mood and anxiety disorders in childhood and adolescence are disabling, distressing, and prevalent and produce added costs to health systems. This two-site randomized controlled trial will test the effects of a brief cognitive behavioral therapy (BCBT) protocol (8-12 sessions) in a large sample (N=210) of children and adolescents (age 8-16) presenting with anxiety and/or depression in primary care. Clinical and cost-effectiveness of BCBT will be compared to a plausible public health alternative - enhanced referral to specialty mental health care (SMHC). This investigation is noteworthy in adopting a deployment-focused model and testing this intervention early in its development within a real world context (primary care) and against a plausible public health comparison condition (SMHC) relevant for future treatment dissemination.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| specialty mental health care referral | Active Comparator |
| |
| Brief Cognitive Behavioral Therapy | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Brief Cognitive Behavioral Therapy (BCBT) | Behavioral | BCBT: 8-12 sessions over 16 weeks of cognitive-behavioral therapy administered by Master's-level clinicians in primary care setting |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical Global Impression | measured at baseline (week 0) | |
| Clinical Global Impression | measured at post-treatment (week 16) | |
| Clinical Global Impression | measured at 8 month follow-up (week 32) |
| Measure | Description | Time Frame |
|---|---|---|
| Pediatric Anxiety Rating Scale | measured at baseline (week 0) | |
| Children's Depression Rating Scale - Revised | measured at baseline (week 0) | |
| Health Utilities Index |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| V. Robin Weersing, Ph.D. | San Diego State University | Principal Investigator |
| David A Brent, M.D. | Western Psychiatric Institute and Clinics | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| San Diego State University | San Diego | California | 92120 | United States | ||
| Western Psychiatric Institute and Clinics |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Weersing VR, Gonzalez A, Campo JV, Lucas AN. Brief behavioral therapy for pediatric anxiety and depression: Piloting an integrated treatment approach. Cognitive and Behavioral Practice 15: 126-139, 2008. | ||
| 36965232 | Derived | Baca SA, Goger P, Glaser D, Rozenman M, Gonzalez A, Dickerson JF, Lynch FL, Porta G, Brent DA, Weersing VR. Reduction in avoidance mediates effects of brief behavioral therapy for pediatric anxiety and depression. Behav Res Ther. 2023 May;164:104290. doi: 10.1016/j.brat.2023.104290. Epub 2023 Mar 8. | |
| 36030033 |
| Label | URL |
|---|---|
| Click here for more information about this study: Brief CBT for Pediatric Anxiety and Depression in Primary Care | View source |
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| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| D003863 | Depression |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| Specialty mental health care referral (SMHC) | Behavioral | SMHC: specialty mental health care referrals provided |
|
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This measure will aid in cost-effectiveness analyses. |
| measured at baseline (week 0) |
| Pediatric Anxiety Rating Scale | measured at post-treatment (week 16) |
| Pediatric Anxiety Rating Scale | measured at 8 month follow-up (week 32) |
| Children's Depression Rating Scale - Revised | measured at post-treatment (week 16) |
| Children's Depression Rating Scale - Revised | measured at 8 month follow-up (week 32) |
| Health Utilities Index | This measure will aid in cost-effectiveness analyses. | measured at post-treatment (week 16) |
| Health Utilities Index | This measure will aid in cost-effectiveness analyses. | measured at 8 month follow-up (week 32) |
| Pittsburgh |
| Pennsylvania |
| 15213 |
| United States |
| Derived |
| Schwartz KTG, Kado-Walton M, Dickerson JF, Rozenman M, Brent DA, Porta G, Lynch FL, Gonzalez A, Weersing VR. Brief Behavioral Therapy for Anxiety and Depression in Pediatric Primary Care: Breadth of Intervention Impact. J Am Acad Child Adolesc Psychiatry. 2023 Feb;62(2):230-243. doi: 10.1016/j.jaac.2022.08.007. Epub 2022 Aug 24. |
| 31278996 | Derived | Brent DA, Porta G, Rozenman MS, Gonzalez A, Schwartz KTG, Lynch FL, Dickerson JF, Iyengar S, Weersing VR. Brief Behavioral Therapy for Pediatric Anxiety and Depression in Primary Care: A Follow-up. J Am Acad Child Adolesc Psychiatry. 2020 Jul;59(7):856-867. doi: 10.1016/j.jaac.2019.06.009. Epub 2019 Jul 3. |
| 28423145 | Derived | Weersing VR, Brent DA, Rozenman MS, Gonzalez A, Jeffreys M, Dickerson JF, Lynch FL, Porta G, Iyengar S. Brief Behavioral Therapy for Pediatric Anxiety and Depression in Primary Care: A Randomized Clinical Trial. JAMA Psychiatry. 2017 Jun 1;74(6):571-578. doi: 10.1001/jamapsychiatry.2017.0429. |
| Click here for more information about this study: Brief CBT for Pediatric Anxiety and Depression in Primary Care | View source |