Trial of Pemetrexed in Combined With Cisplatin for the Treatment of Advanced Breast Cancer

Trial of Pemetrexed in Combined With Cisplatin for the Treatment of Advanced Breast Cancer

For patients resistant to enthrycycline and taxanes, there is no standard regimen. Pemetrexed alone had certain efficacy in treatment of advance breast cancer. Platin was also a effective drug for advanced breast cancer. The combination of these two drug may have a synergy with each other in treatment of advanced breast cancer.

combination of pemetrexed and cisplatin to treat advanced breast cancer. Previous regimen no more than 3 which including enthrycycline and taxanes(paclitaxel and/or docetaxel)

Inclusion Criteria:

• 18-70 years old
• Resistant to enthracycle and taxanes
• Has measurable disease

Exclusion Criteria:

• Has more than 3 previous chemotherapy regimens