Chlorhexidine Mouthrinses and Plaque Control

Chlorhexidine Alcohol Base Mouthrinse Versus Chlorhexidine Formaldehyde Base Mouthrinse Efficacy on Plaque Control: Double Blind, Randomized Clinical Trials

The aim of the present study was to compare antiplaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F).

Chlorhexidine (CLX) mouthrinse has been the gold standard as antiplaque solution.However, if its efficiency seems to be preserved even if the chlorhexidine concentration is bellow 0.10%, the formulation of the final product may affect the effectiveness. Thus, it can be concluded from this study that 0.12% CLX alcohol base mouthrinse is significantly more effective in inhibiting plaque than the diluted 0.1% CLX non-alcohol base containing formaldehyde mouthrinse.

Inclusion Criteria:

• give written informed consent before entering the study
• accept to stop tooth cleaning for a week

Exclusion Criteria:

• less than 20 teeth;
• presence of periodontal disease
• presence of factors of plaque retention (clinically unacceptable restorations, important carious, dental overlapping, removable prosthesis, faulty fixed prosthesis, orthodontic appliances),
• associated systemic diseases (diabetes, heart disorders, blood diseases, HIV infection),
• use of antibiotics or other anti-inflammatory drugs during the latest months,
• known allergy against components of mouth rinses,
• pregnancy,
• smoking