Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Adult and Adolescent Subjects With Perennial Allergic Rhinitis (PAR)

A Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group, 6-Week Study Designed to Investigate the Effects of BDP HFA Nasal Aerosol on the Hypothalamic-Pituitary-Adrenal (HPA) Axis When Administered in Adolescent and Adult Subjects (12 to 45 Years of Age) With Perennial Allergic Rhinitis (PAR)

The purpose of the study is to evaluate the effects of BDP HFA Nasal Aerosol on HPA-axis function.

Inclusion Criteria:

• Informed Consent
• Male or female subjects 12-45 years of age
• Documented history of perennial allergic rhinitis
• General good health
• Other criteria apply

Exclusion Criteria:

• History of physical findings of nasal pathology (within 60 days prior to Screening Visit 1)
• Participation in any investigational drug study 30 days preceding Screening Visit 1
• History of respiratory infection/disorder with 14 days preceding Screening Visit 1
• Use of any prohibited concomitant medications