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The purpose of this study is to collect standardized data on the diagnosis and management of idiopathic (unknown cause) recurrent acute pancreatitis. The intent is to collect data for at least five years to obtain information regarding long-term outcomes and obtain comparative effectiveness data.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pancreatitis, acute, recurrent | Patients with acute recurrent pancreatitis where the cause is unknown |
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| Measure | Description | Time Frame |
|---|---|---|
| IDIOPATHIC RECURRENT ACUTE PANCREATITIS (IRAP) | Expect 750 to be treated with ERCP Expect 250 to be treated with conservative treatment. Therefore, the smaller group was used for the sample size analysis. Smallest difference in QOL for treatment is expected to be 10-20%. For smaller of two treatment groups (N=250), no effect would be 0 got better and 250 did not. If 10% of the subjects improved, 25 would get better and 225 would not. Result: Chi-square analysis yielded a highly significantly difference as follows. Chi-square= 24.253 with 1 degrees of freedom. (P = <0.001). Yates correction for continuity was used in calculating this test.An alternate analysis is that for no effect, 125 subjects would get better and 125 patients would not (random effects model). | The goal is to recruit 1000 subjects in 5 years. |
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Inclusion Criteria:
Note: subjects with a diagnosis of pancreas divisum and or Sphincter of Oddi dysfunction diagnosed prior to or after entry into the study will be included in the study but their data will be analyzed separately because of the controversy regarding the association of these entities with pancreatitis.
Exclusion Criteria:
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Subjects with recurrent pancreatitis presenting to major centers for pancreatic disorders
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| Name | Affiliation | Role |
|---|---|---|
| Nalini M Guda, MD | Wake Forest University Health Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aurora St. Lukes Medical Center of Aurora Health Care | Milwaukee | Wisconsin | 53215 | United States |
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| ID | Term |
|---|---|
| D010195 | Pancreatitis |
| ID | Term |
|---|---|
| D010182 | Pancreatic Diseases |
| D004066 | Digestive System Diseases |
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