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Pain relapse during oral refeeding occurs in at least one-fifth of patients with acute pancreatitis. The study hypothesis is that early administered enteral tube feeding might reduce a risk of pain relapse and shorten the length of hospital stay in patients with acute pancreatitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Enteral tube feeding | Other | Nasogastric tube feeding started within 24 h of hospital admission |
|
| Nil-per-mouth regimen | No Intervention | Conventional management |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Enteral tube feeding | Procedure | Nasogastric tube feeding started within 24 h of hospital admission |
|
| Measure | Description | Time Frame |
|---|---|---|
| Length of hospital stay | Up to 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Pain relapse | Up to 3 months | |
| Local and systemic complications | Up to 3 months | |
| Feeding intolerance |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Max Petrov, MD, MPH (Epi) | Universioty of Auckland | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Auckland | Auckland | New Zealand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17686077 | Background | Petrov MS. Enteral nutrition: goody or good-for-nothing in acute pancreatitis? Am J Gastroenterol. 2007 Aug;102(8):1828-9; author reply 1829-30. doi: 10.1111/j.1572-0241.2007.01361.x. No abstract available. | |
| 17573797 | Background | Petrov MS, van Santvoort HC, Besselink MG, Cirkel GA, Brink MA, Gooszen HG. Oral refeeding after onset of acute pancreatitis: a review of literature. Am J Gastroenterol. 2007 Sep;102(9):2079-84; quiz 2085. doi: 10.1111/j.1572-0241.2007.01357.x. Epub 2007 Jun 16. |
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| ID | Term |
|---|---|
| D010195 | Pancreatitis |
| ID | Term |
|---|---|
| D010182 | Pancreatic Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D004750 | Enteral Nutrition |
| ID | Term |
|---|---|
| D005248 | Feeding Methods |
| D013812 | Therapeutics |
| D018529 | Nutritional Support |
| D044623 | Nutrition Therapy |
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| Up to 3 months |
| Time to solid oral food tolerated | Approx. one week |
| Pain-free time | Up to 3 months |
| Hospital readmission | Up to 6 months |
| Quality of life | Up to 6 months |
| Mortality | Up to 6 months |
| 18331767 | Background | Petrov MS. To feed or not to feed early in acute pancreatitis: still depend on severity? Clin Nutr. 2008 Apr;27(2):317-8. doi: 10.1016/j.clnu.2008.01.011. Epub 2008 Mar 10. No abstract available. |
| 23340042 | Derived | Petrov MS, McIlroy K, Grayson L, Phillips AR, Windsor JA. Early nasogastric tube feeding versus nil per os in mild to moderate acute pancreatitis: a randomized controlled trial. Clin Nutr. 2013 Oct;32(5):697-703. doi: 10.1016/j.clnu.2012.12.011. Epub 2012 Dec 31. |