MIld to MOderate Acute Pancreatitis: Early naSogastric Tube Feeding Compared With pAncreas Rest (MIMOSA)

Early Enteral Tube Feeding Compared With Pancreas Rest in Patients With Acute Pancreatitis: a Randomized Controlled Trial

Pain relapse during oral refeeding occurs in at least one-fifth of patients with acute pancreatitis. The study hypothesis is that early administered enteral tube feeding might reduce a risk of pain relapse and shorten the length of hospital stay in patients with acute pancreatitis.

Inclusion Criteria:

• diagnosis of acute pancreatitis
• age 18 years or older
• written informed consent

Exclusion Criteria:

• > 96 hours after onset of symptoms
• > 24 hours after hospital admission
• organ failure by the time of randomization
• infectious complications before randomization
• received artificial nutrition before randomization
• previously enrolled into the trial
• chronic pancreatitis
• post-ERCP pancreatitis
• intraoperative diagnosis of acute pancreatitis
• pregnancy
• malignancy