This is a prospective, single-center, randomized, controlled, open-label, pilot study to evaluate the effectiveness of high dose statin loading in acute heart failure patients.

Inclusion Criteria:

• Dyspnea at rest or minimal activity
• Tachypnea (respiratory rate > 20/min) or rales or pulmonary edema on chest X-ray

Exclusion Criteria:

• Acute coronary Syndrome
• Hospitalization plan for PTCA or CABG
• Cardiogenic shock (Systolic Blood Pressure < 80mmHg)
• Uncontrolled hypertension (Systolic Blood Pressure > 180mmHg)
• Allergy, adverse drug reaction, hypersensitivity to statin
• Troponin > 5 times upper limit of normal (ULN)
• Creatinine kinase-MB level > 3 times ULN
• AST, ALT > 3 times ULN or acute hepatitis
• Current or past history of muscle disease, rhabdomyolysis
• Life expectancy < 6 months (e.g. metastatic malignancy, liver cirrhosis)
• Pregnancy or women at age of childbearing potential