Patients in this group are treated with usual therapeutic endoscopy including endoscopic combination therapy and 72 hours intravenous proton pump inhibitor. Within 24 hours from the therapeutic endoscopy they receive supplementary angiographic embolization.

Patients in this arm receive standard treatment including therapeutic endoscopy with endoscopic combination therapy followed by 72 hours intravenous proton pump inhibitor.

Patients in the intervention arm receive supplementary angiographic embolization within 24 hours from the therapeutic endoscopy.

Patients are classified into groups depending on the worst outcome:

1. No clinical signs of rebleeding and requirement of two or less blood transfusions after circulatory stabilization and obtained hemoglobin > 5,9mmol/L.
2. No clinical signs of rebleeding and requirement of more than two blood transfusions after circulatory stabilization and obtained hemoglobin > 5,9mmol/L.
3. Rebleeding and achieved secondary haemostasis by endoscopy or angiographic embolization.
4. Rebleeding requiring surgery.
5. Patients who have died.

Results are compared using the Wilcoxon rank sum test.

Patients who have died within af month from therapeutic endoscopy.

Rebleeding from ulcer confirmed by endoscopy, angiography or surgery within a month from therapeutic endoscopy.