Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Florida A&M University | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Fish can provide pregnant women with omega-3 fatty acids for fetal brain development but some fish contains high levels of mercury which is detrimental to fetal brain development. The hypothesis is that women who have previously consumed high mercury fish can reduce the mercury level in their bodies and improve their omega-3 levels in three months by eating fish that is high in omega-3 fatty acids and low in mercury.
Exposure to methylmercury, a developmental toxicant found primarily in fish. Fish is nutritionally important for providing long chain omega-3 fatty acids that are important for perinatal health. Since maternal transfer of mercury and omega-3 fatty acids are the primary routes for fetal (placental transfer) or infant (maternal milk) exposure, there is a critical need to develop specific advice for childbearing-aged women based upon the 2004 Dietary Guidelines Advisory Committee's recommended intake i.e., consume 8 ounces of fish per week. This clinical trial investigates whether weekly consumption of selected fish species for 12 weeks can improve plasma concentrations of the omega-3 fatty acids (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) while reducing hair or blood mercury concentrations.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tilapia | Active Comparator | Subjects are fed 6 oz tilapia once a week for 3 months |
|
| Salmon | Active Comparator | Subjects fed 6 oz salmon once a week for 3 months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Feeding low mercury fish | Other | Subjects fed 6 oz of either tilapia (low omega-3 fish) or salmon (high omega-3 fish) for 3 months. Both fish are low in mercury |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hair Mercury | The hair mercury after feeding low mercury fish for 3 months | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Blood mercury concentration | The blood mercury concentration after feeding low mercury fish for 3 months | 3 months |
| Blood omega-3 fatty acid concentrations | Blood omega-3 fatty acid concentration after feeding either salmon or tilapia for 3 months |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Charles Santerre, Ph.D | Purdue University, Department of Foods and Nutrition | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Florida A&M University | Tallahassee | Florida | 32307-4100 | United States | ||
| Purdue University, Department of Foods and Nutrition |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 3 months |
| West Lafayette |
| Indiana |
| 47907-2059 |
| United States |