Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to evaluate the long term clinical impact of routine follow-up coronary angiography after percutaneous coronary intervention (PCI). The primary endpoint is a composite of death/myocardial infarction/stroke/emergency hospitalization for acute coronary syndrome/hospitalization for congestive heart failure at 3-year after percutaneous coronary intervention.
Routine follow-up coronary angiography after percutaneous coronary intervention has been performed to detect restenosis in a lot of PCI centers in Japan. On the other hand, previous studies reported that routine follow-up coronary angiography might lead to unnecessary reinterventions in asymptomatic patients. In this situation, the effect of routine follow-up coronary angiography on long-term clinical outcomes remains unknown. The purpose of this study is to evaluate the long-term clinical impact of routine follow-up coronary angiography after PCI compared with clinical follow-up alone. The primary endpoint of this study is a composite of death/myocardial infarction/stroke/emergency hospitalization for acute coronary syndrome/hospitalization for congestive heart failure at three-year after percutaneous coronary intervention. The design of this study is almost all-comer design enrolling patients received PCI without any exclusion criteria.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| routine follow-up coronary angiography | Active Comparator | routine follow-up coronary angiography at 8-12 after discharge for percutaneous coronary intervention |
|
| clinical follow-up | Active Comparator | no routine follow-up coronary angiography at 8-12 after discharge for percutaneous coronary intervention |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| follow-up coronary angiography | Procedure | follow-up coronary angiography at 8-12 months after discharge for percutaneous coronary intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| a composite of death/myocardial infarction/stroke/emergency hospitalization for acute coronary syndrome/hospitalization for congestive heart failure | a composite of death/myocardial infarction/stroke/emergency hospitalization for acute coronary syndrome/hospitalization for congestive heart failure | 4.8 years |
| Measure | Description | Time Frame |
|---|---|---|
| death | death | 4.8 years |
| cardiac death | cardiac death | 4.8 years |
Not provided
Inclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Takeshi Kimura, MD | Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Division of Cardiology, Kyoto University Hospital | Kyoto | Kyoto | 606-8507 | Japan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28040445 | Derived | Shiomi H, Morimoto T, Kitaguchi S, Nakagawa Y, Ishii K, Haruna Y, Takamisawa I, Motooka M, Nakao K, Matsuda S, Mimoto S, Aoyama Y, Takeda T, Murata K, Akao M, Inada T, Eizawa H, Hyakuna E, Awano K, Shirotani M, Furukawa Y, Kadota K, Miyauchi K, Tanaka M, Noguchi Y, Nakamura S, Yasuda S, Miyazaki S, Daida H, Kimura K, Ikari Y, Hirayama H, Sumiyoshi T, Kimura T; ReACT Investigators. The ReACT Trial: Randomized Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial. JACC Cardiovasc Interv. 2017 Jan 23;10(2):109-117. doi: 10.1016/j.jcin.2016.10.018. Epub 2016 Dec 28. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Clinical follow-up | Procedure | no routine follow-up coronary angiography at 8-12 months after discharge for percutaneous coronary intervention |
|
| myocardial infarction |
myocardial infarction |
| 4.8 years |
| stent thrombosis | stent thrombosis defined bya Academic Reseach Consortium | 4.8 years |
| stroke | both ischemic and hemorrhagic stroke excluding transient ischemic attach | 4.8 years |
| bleeding complications | bleeding complications defined by GUSTO and TIMI | 4.8 years |
| any coronary revascularization | any coronary revascularization | 4.8 years |
| clinically-driven coronary revascularization | clinically-driven coronary revascularization | 4.8 years |
| clinically-driven target-lesion revascularization | clinically-driven target-lesion revascularization | 4.8 years |
| any target-lesion revascularization | any target-lesion revascularization | 4.8 years |
| coronary artery bypass grafting | coronary artery bypass grafting | 4.8 years |
| angina | angina | 4.8 years |
| renal function | estimate-glomerular filtration rate | 4.8 years |
| emergency hospitalization for acute coronary syndrome | emergency hospitalization for acute coronary syndrome | 4.8 years |
| hospitalization for congestive heart failure | hospitalization for congestive heart failure | 4.8 years |
| composite of cardiac death, myocardial infarction or acute coronary syndrome | composite of cardiac death, myocardial infarction or acute coronary syndrome | 4.8 years |
| follow-up coronary angiography | presence of follow-up coronary angiography | 4.8 years |
| clinically-driven follow-up coronary angiography | presence of clinically-driven follow-up coronary angiography | 4.8 years |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |