This study will evaluate the Area Under the Curve (AUC(0 to infinity)) of anacetrapib in subjects with impaired renal function and healthy matched control subjects.

Inclusion Criteria:

• Female subjects of reproductive potential test negative for pregnancy and agree to use two acceptable methods of birth control throughout the study
• Subject is in good health
• If Subject is a smoker, smoking is limited to no more than 10 cigarettes per day

Exclusion Criteria:

• Subject has a history of stroke, chronic seizures or major neurological disorder
• Subject has a history of cancer
• Subject is unable to refrain from or anticipates the use of any prescription or non-prescription medication during the study
• Subject consumes excessive amounts of alcohol or caffeine
• Subject has had major surgery, donated blood or participated in another investigational study within the past 4 weeks
• Subject is a nursing mother
• Subject has had a kidney removed or has a functioning renal transplant