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Recurrent aphthous stomatitis is a difficult to treat and quite common chronic inflammatory disease of the oral mucosa. This study evaluates the fluid extract from Chamomilla recutita's safety and effectiveness in treatment of aphthous stomatitis .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| chamomilla tincture mouthwash | Active Comparator | Chamomile comprises bisaboloids, matricine and chamazulene, flavonoids, and cumarins having therapeutical anti-inflammatory, analgesic, musculotropic, and spasmolytic action |
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| placebo mouth wash | Placebo Comparator | placebo mouthwash is produced with the same taste and smell for using in placebo/ control group. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| chamomilla tincture mouthwash | Drug | The patient is directed to mouth wash chamomilla tincture lightly three times a day,ten drops for each time,until ulcers completely heal |
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| Measure | Description | Time Frame |
|---|---|---|
| protocol designed to evaluate the effect of fluid extract from Chamomilla recutita's on treatment of aphthous stomatitis | This study evaluates the fluid extract from Chamomilla recutita's effectiveness on healing rate of aphthous stomatitis, and reducing ulcer size | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| This study aimed to evaluate the efficacy of chamomile mouthwash of decreasing the pain and frequency of oral aphthous ulcer | In the present work the Analogical Visual Scale is used TO evaluate pain,and we also record the frequency of ulcers monthly | 3 months |
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Inclusion Criteria:• Confirmation of clinical diagnosis of aphthae
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| seyyed amir seyyedi, DDS-MSc | mashhad UMS | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mashhad University of Madical Science,Research Center of Mashhad Dental School | Mashhad | Razavi Khorasan Province | 91735 | Iran |
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| ID | Term |
|---|---|
| D013281 | Stomatitis, Aphthous |
| ID | Term |
|---|---|
| D013280 | Stomatitis |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| placebo mouthwash | Drug | The patient is directed to use placebo mouthwash three times a day, ten drops for each time,until the ulcers completely heal |
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