Continuous positive airway pressure (CPAP) is the most commonly used treatment for obstructive sleep apnea. Nasal symptoms such as dryness, itching and congestion are common in CPAP users. Nasal and sinus saline irrigation has been shown to improve these symptoms in individuals with chronic nasal congestion and sinusitis. This is an 8 week study that investigates whether daily saline nasal and sinus irrigation reduces nasal symptoms in patients using CPAP, improves quality of life and CPAP compliance.

Inclusion Criteria:

• Age ≥ 18
• Apnea/hypopnea index ≥ 10
• A documented successful CPAP titration

Exclusion Criteria:

• Conditions that in the judgment of the investigator would interfere with subject participation in the study
• History of sinus or nasal surgery
• History of psychiatric illness
• Use of sleep aids, sedatives or narcotics
• Use of oral of subcutaneous anti-coagulants (i.e. warfarin, enoxaparin)
• Bilevel or other nocturnal ventilation other than CPAP
• Use of supplemental oxygen
• Pregnancy or lactating
• Inability or unwillingness to provide informed consent
• Inability to perform baseline measurements
• Inability to be contacted by phone