Study of the Inflammatory Reaction in Standard vs Single Port Cholecystectomy for Uncomplicated Cholelithiasis

Study of the Inflammatory Reaction in Standard vs Single Port Cholecystectomy for Uncomplicated Cholelithiasis

This is a study of the inflammatory reaction in standard 4 port laparoscopic cholecystectomy vs Single Port Laparoscopic (SIL) cholecystectomy. It is assumed that the reduced trauma in SIL Cholecystectomy causes reduced inflammatory reaction compared to the 4 port laparoscopic cholecystectomy.

Two groups of 20 patients each are included in this study. Pre operatively, 6 and 24 hours postoperatively, blood is taken from these patients, it is centrifuged and the plasma is taken. IL-6, a-defensins and CRP are measured for each sample.

Inclusion Criteria:

• Uncomplicated cholelithiasis
• American Society of Anesthesiologists (ASA) I or II
• No previous operations in upper abdomen
• Body mass index (BMI) <30

Exclusion Criteria:

• Cholecystitis
• ASA > II
• BMI>30
• Previous operations in upper abdomen
• Previous operations in intestine