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The purpose of this study is to determine the effect of high sn-2 palmitic acid based infant formula on intestinal parameters in term formula fed infants.
InFatTM is an advanced basic-fat ingredient, which mimics the fat composition and properties of human milk fat and enabling optimal intake of the essential calcium and energy (in the form of fatty acids) and easy digestion. These benefits are the result of a unique fatty acid composition on the glycerol backbone, which ensures high level of palmitic acid at the middle (sn-2) position.
The purpose of this study is to determine the effect of high sn-2 palmitic acid based infant formula on intestinal parameters, anthropometric parameters and stool characteristics in formula fed term infants.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard vegetable oil based formula | Active Comparator |
| |
| InFatâ„¢ based infant formula | Active Comparator |
| |
| Breast-fed | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| InFatâ„¢ based infant formula | Other | High sn-2 palmitic acid oil based infant formula |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intestinal flora composition | infant feces microbial analysis | Baseline, 5 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Anthropometric measurements | Body length, weight, and head circumferences | Baseline, 5 weeks |
| General Health and Well being | Physical examinations, Health (dieases, doctor visits) and well being (sleeping, crying) questionnaires, medications report |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Arie Riskin, MD | Bnai Zion Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bnai Zion Medical center | Haifa | Israel |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23201699 | Derived | Yaron S, Shachar D, Abramas L, Riskin A, Bader D, Litmanovitz I, Bar-Yoseph F, Cohen T, Levi L, Lifshitz Y, Shamir R, Shaoul R. Effect of high beta-palmitate content in infant formula on the intestinal microbiota of term infants. J Pediatr Gastroenterol Nutr. 2013 Apr;56(4):376-81. doi: 10.1097/MPG.0b013e31827e1ee2. |
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| ID | Term |
|---|---|
| D015438 | Health Behavior |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| Standard vegetable oil based infant formula | Other | Standard vegetable oil based infant formula |
|
|
| Baseline, 5 weeks |