Multiple Ascending Dose Study for AZD 7268 in Japanese Healthy Male Volunteers

A Phase I, Single-Centre, Randomised, Double-Blind, Placebo-controlled, Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7268 When Given in Multiple Ascending Oral Doses in Japanese Healthy Male Subjects

This is a multiple ascending dose study (MAD) in the Japanese population with AZD7268. This MAD study will evaluate the safety, tolerability and pharmacokinetics of orally administered AZD7268 after multiple ascending doses.

Inclusion Criteria:

• Provision of Informed Consent
• Healthy male subjects, with suitable veins for cannulation or repeated venipuncture

Exclusion Criteria:

• Inability to understand or cooperate with given information
• Any positive result on screening for human immune deficiency virus (HIV), Hepatitis B, Hepatitis C and syphilis test
• History of seizure (including infant febrile seizures) or family history of seizure