Components of Chlorhexidine Gluconate Dressing

Components & Tolerability of Chlorhexidine Gluconate Dressing Patch Compared to BioPatch & Tegaderm Chlorhexidine Gluconate Securement Dressing After Application to Healthy Subjects Over a 7-day Period

The purpose of this study is to determine the contents of a chlorhexidine-containing dressing after use.

To characterize the chemical composition of the CHG (2% CHG) Catheter Dressing Patch as compared to Biopatch Protective Disk with CHG, and Tegaderm IV (intravenous) Securement Dressing over a wear period of 7 days.

Inclusion Criteria:

• Able to read, review and sign the Informed Consent
• Willing to shower using the same soap/cleansers from the Screening Visit through the end of the study
• Use study-approved contraceptive methods

Exclusion Criteria:

• Participation in an investigational study within 28 days prior to dosing.
• Clinically significant illness within 28 days prior to dosing.
• History of allergic responses to chlorhexidine, chlorhexidine-containing products, glycerol, adhesives, latex
• History of clinically significant skin disorders
• History of Type I diabetes mellitus, insulin-dependent diabetes mellitus(IDDM)
• History of significant dermatologic cancers (melanoma, squamous)
• Known history of immunologic disorders
• Use immunosuppressive or other proscribed medications
• Use of skin products at the application site
• Significant history of allergies to soaps, lotions, emollients, ointments, creams
• History of drug or alcohol addiction within the past year
• Pregnant, lactating, breast-feeding, or intends to become pregnant during the course of the study