The main objective is to investigate the incidence of Respiratory Tract Infections (RTIs) and antibiotic prescriptions in children and during pregnancy, the different drugs chosen by their doctors according to diagnosis, and compliance by patients. Further to investigate the possible effect of antibiotic use during pregnancy on RTIs and antibiotics and respiratory drug prescriptions in children the first two years after birth.

Specific study objectives:

• RTIs and antibiotic prescriptions in pre-school children

  • Frequency of diagnoses and antibiotic prescriptions
  • The proportion of broad spectrum antibiotics chosen

• Prescription patterns and treatment compliance during pregnancy

  • Incidence of diagnoses, compared with not pregnant patients
  • Choice of antibiotics in RTIs
  • Prescription collection from pharmacies

• Antibiotics and respiratory medication in children aged 0-2 yrs

  • Compare prevalence in children of mothers with frequent RTIs/antibiotic prescriptions during pregnancy and prevalence in children of mothers with few or no consultations during pregnancy
  • Incidence of wheezing and asthma diagnoses and incidence og respiratory prescription drugs when the mother has received antibiotics in pregnancy

Inclusion Criteria:

• Contact with general practitioner in the time of registration

Exclusion Criteria:

• Men (except children aged 0-2 yrs)
• Women in ages 2-14 and above 60 yrs

Contacts with general practitioner in different parts of Norway. Women aged 15-60 yrs and children 0-2 yrs are selected.