The purpose of this study is to evaluate the Efficacy and Safety of Dehypotin® in the Patients with Type 2 Diabetes Mellitus or Cardiovascular Disease. Eligible patients will be randomly assigned to 1 of 2 arms, either Dehypotin® or placebo, and will receive the diet advisement throughout the study.

Inclusion Criteria:

• Male or female
• Age 20-75 years
• Diagnosis of type II Diabetes Mellitus for at least 3 months and/or clinical evident cardiovascular disease (CVD)
• A hemoglobin A1c concentration has to be < 8% before screening

Exclusion Criteria:

• Women of child bearing potential who are pregnant, breastfeeding or not using effective contraceptives
• Known hypersensitivity to Pravastatin or any of its components
• Have a history of homozygous familial hypercholesterolemia or known type III hyperlipoproteinemia
• Significant medical illness
• Known serious conditions, e.g. serum creatine kinase(CK)levels 2.5 times upper limit of normal
• Subjects being treated with drugs influence serum lipid concentrations
• Subjects who have cancer or been receiving the cancer chemotherapy