Prevention of Catheter-Associated Urinary Tract Infection in Incontinence and Reconstructive Pelvic Surgery Patients

Prevention of Catheter-Associated Urinary Tract Infections in Patients Undergoing Incontinence and Reconstructive Pelvic Surgery: A Randomized Controlled Trial

The study will assess the risk of catheter associated urinary tract infection in women undergoing incontinence or reconstructive pelvic surgery. Women will be given an antibiotic or placebo at the time of catheter removal. The investigators hypothesize that prophylactic antibiotics will reduce the rate of infection.

Inclusion Criteria:

• Requires catheterization >24h hours following incontinence or pelvic reconstructive surgery

Exclusion Criteria:

• Receipt of antibiotics for either prophylaxis or treatment of a known infection during the postoperative hospitalization
• Allergy to sulfonamides or trimethoprim
• Non-English speaking
• Pregnancy
• Breast feeding
• Severe renal impairment (creatinine clearance <30)
• Patients taking dofetilide, methenamine, procaine, warfarin, procainamide, methotrexate.