Dengue Seroprevalence Study in Blood Donors in the French West Indies

Dengue Seroprevalence Study in Blood Donors in the French West Indies

Dengue is an infectious disease most prevalent in the world. This disease is endemic in the Caribbean, with an increase in seasonal rains. Several outbreaks have been observed in recent years, in 2001, 2005 and 2007, during which further particularly virulent serotypes have emerged. The clinical expression of dengue fever is variable, ranging from no symptoms to a classical form with fever, and even of severe or lethal bleeding. With the possible existence of silent forms of the disease, there are no data identifying the current level of protection of the population in Martinique / Guadeloupe.

1. Principal objective:

   To estimate the prevalence of the specific antibodies of the dengue (IgG) in blood donors in the French West Indies.

2. Secondary objective:

To specify the serotypic specificity of the anti-dengue antibodies detected during the study.

Inclusion Criteria:

• Eligible for blood donation following the French legislation,
• Resident in Martinique /Guadeloupe for at least one year
• Consent signed

Exclusion Criteria:

• Not Eligible for blood donation following the French legislation,
• Not Resident in Martinique / Guadeloupe for at least one year
• Consent not signed