The purpose of this study is to verify and validate the intrinsic diagnostic value in terms of sensitivity and specificity of proteomic profiles determined during a pre-study for discriminating between allergy related asthma and allergy related rhinitis.

Inclusion Criteria:

• signed consent
• never-smokers or non-smoking for at least 2 years + < 5 packs per year
• capable of understanding the study
• patient is affiliated with a social security system
• positive skin tests (at least one for Montpellier region pneumoallergens)
• treated with nasal or inhaled corticoids, leucotriene receptor antagonists, anti-IgE, Theophylline, anti-histamines, sodium cromoglycate, beta-blockers, benzodiazépine, oral corticoids: all these treatments must be interrupted for at least 72 hours

Exclusion Criteria:

• Co-morbidities: none; no co-morbidities are accepted
• dental infections (any) during the 3 months preceding the study
• suspected alcoholism or drug abuse
• chronic viral infection (hepatitis, HIV)
• patient under guardianship

The asthma and allergic rhinitis patients included in this study are recruted from the Pneumology Departments of the University Hospitals of Nîmes, Marseilles, and Montpellier.