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| Name | Class |
|---|---|
| Arla Foods | INDUSTRY |
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The aim of this study is to determine the effect of cultura yoghurt on transit time and digestive discomfort during 2 weeks of treatment in comparison to placebo in healthy women and men.
Transit time is the time it takes for a substance to pass through the gut. The major part of the transit is spent in the large bowel is therefore mainly a colonic event. It has been observed that slow transit time is associated with high prevalence of large bowel disorders. The objectives of this study is to:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yoghurt without probiotics | Placebo Comparator | Yoghurt without probiotic bacteria |
|
| Cultura yoghurt | Active Comparator | Cultura yoghurt with L casei F19, acidophilus La5 adn B lactis Bb 12 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cultura L casei F19, acidophilus La5 , B lactis Bb 12 | Other | 2 weeks consumption,250 ml/day |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in transit time between treatments | To determine the effect on mean transit time after 2 weeks intake of investigational products using radio-opaque barium sulphate impregnated polyethylen capsules. These capsules will be consumed during 3 days and thereafter an x-ray image will be taken over the bowel. The capsulese will then be calculated to determine the colonic transit time | February 2010-June 2010 |
| Measure | Description | Time Frame |
|---|---|---|
| Change between treatments on Bristol Stool Form (BSF)symptoms scores | To determine the effect of Cultura yoghurt on the total symptom score according to Bristol Stool Form (BSF) scale during 2 weeks of treatment in comparison to placebo in healthy women and men | February 2010-June2010 |
| Change between treatments on gastrointestinal symptoms according to Bristol Stool Form |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lars Magnusson, CEO | Good Food Practice, Uppsala, Sweden | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Good Food Practice | Uppsala | 751 83 | Sweden |
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| ID | Term |
|---|---|
| D003248 | Constipation |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D015014 | Yogurt |
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D043302 | Cultured Milk Products |
| D008892 | Milk |
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
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| Yoghurt without probiotics | Other | Yoghurt without probiotics |
|
To determine the effect of Cultura yoghurt on gastrointestinal symptoms according to the Bristol Stool Form (BSF) after 2 weeks treatment of investigational products |
| February 2010-June 2010 |
| D010829 |
| Physiological Phenomena |
| D000074421 | Fermented Foods |
| D003611 | Dairy Products |
| D005502 | Food |
| D019602 | Food and Beverages |
| D019587 | Dietary Supplements |