Dialysis catheters are sites of bacterial proliferation. The purpose of this study is to determine whether or not the use of Taurolock (a catheter lock solution) can prevent bacterial peritonitis in patients undergoing peritoneal dialysis.

Inclusion Criteria:

• 18 years or older
• Renal insufficiency, stage V (HAS 2007 classification)
• Requires incident peritoneal dialysis
• No signs of peritoneal infection on inclusion
• signed consent
• affiliated with a social security system

Exclusion Criteria:

• Patient will have a renal transplant in the upcoming year following dialysis
• Survival prognosis for one year is weak
• allergy to citrate, (cyclo)-taurolidine, or heparin
• patient is taking medication with a known contra-indication with citrate or (cyclo)-taurolidine
• patient has a thrombopenia caused by heparin
• impossible to inform the patient correctly
• patient under guardianship
• patient already included in another biomedical research protocol
• no signed consent
• no social security system