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| ID | Type | Description | Link |
|---|---|---|---|
| 2009-A01310-57 | Other Identifier | Afssaps |
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| Name | Class |
|---|---|
| Groupe Hospitalier Pitie-Salpetriere | OTHER |
Prospective observational clinical multicentric study in ICU with ventilated patients requiring chest ultrasound analysis.
Prospective observational clinical multicentric study on ICU ventilated patients requiring chest ultrasound analysis during weaning from mechanical ventilation with 48 hours of follow-up. Studying variations of cardiac markers
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients requiring ventilation | |||
| patients who weaned permanently |
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| Measure | Description | Time Frame |
|---|---|---|
| Compare the change in pulmonary aeration during the test of weaning from mechanical ventilation (before, at the end, and 4-6 h after) between patients requiring re-ventilation before the 48th hour, and those weaned permanently. | Compare the change in pulmonary aeration during the test of weaning from mechanical ventilation (before, at the end, and 4-6 h after) between patients requiring re-ventilation before the 48th hour, and those weaned permanently. | before, at the end, and 4-6 h after |
| Measure | Description | Time Frame |
|---|---|---|
| Studying variations, during weaning from mechanical ventilation, of pressure of left ventricle filling (E / Ea) coupled with those of plasma BNP. | Studying variations, during weaning from mechanical ventilation, of pressure of left ventricle filling (E / Ea) coupled with those of plasma BNP. | in the 4-6 early hours |
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Inclusion Criteria:
- Adult patients ventilated more than 48 h
Exclusion Criteria:
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Prospective observational clinical multicentric study on ICU ventilated patients requiring chest ultrasound analysis during weaning from mechanical ventilation with 48 hours of follow-up. Studying variations of cardiac markers
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| Name | Affiliation | Role |
|---|---|---|
| Sébastien PERBET | University Hospital, Clermont-Ferrand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Clermont-Ferrand | Clermont-Ferrand | 63003 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23724022 | Derived | Jabaudon M, Perbet S, Pereira B, Soummer A, Roszyk L, Guerin R, Futier E, Lu Q, Bazin JE, Sapin V, Rouby JJ, Constantin JM. Plasma levels of sRAGE, loss of aeration and weaning failure in ICU patients: a prospective observational multicenter study. PLoS One. 2013 May 27;8(5):e64083. doi: 10.1371/journal.pone.0064083. Print 2013. |
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| Assessing the effects of E / Ea and BNP variations on the success or failure in the 4-6 early hours. |
Assessing the effects of E / Ea and BNP variations on the success or failure in the 4-6 early hours. |
| in the 4-6 early hours. |
| Compare the variations of lung ultrasound score during the test of the weaning from mechanical ventilation between patients failed the spontaneous breathing test (SBT) and those extubated after successful SBT. | Compare the variations of lung ultrasound score during the test of the weaning from mechanical ventilation between patients failed the spontaneous breathing test (SBT) and those extubated after successful SBT. | in the 4-6 early hours |
| Comparison of levels epithelial and endothelial markers | at h0, h1, h4, h6 |
| Constitution serum bank for epithelial (sRAGE) markers dosages | at h0, h1, h4, h6 |
| constitution serum bank for endothelial (angiopoietin) markers dosages | at h0, h1, h4, h6 |