For the assessment of the Clinical Global Impression of Change (CGI-C), the investigator provided his/her assessment of the subject's clinical status compared to Baseline. He/she was asked to check the category that best describes the subject's condition over the past 6 months compared to Baseline:

• Very much improved
• Much improved
• Minimally improved
• No change
• Minimally worse
• Much worse
• Very much worse

Of the 520 subjects in the Full Analysis Set (FAS), 515 subjects are included in the analysis of this outcome measure.

FAS comprises all subjects who have been treated with Vimpat® at least once, who fulfill the inclusion criteria and for whom a valid baseline and post-baseline value of seizure frequency is available.

Baseline values for the seizure frequency (SF) during the 12 weeks time period prior to inclusion ('historical baseline'), and the post-baseline values of seizure frequency reported after 3 months were normalized to a 28 days interval.

Change in number of partial-onset seizures was derived as follows:

Change in SF per 28 days = (SF at 3 months per 28 days) - (SF at Baseline per 28 days).

A negative value in change from Baseline means that the value has decreased from Baseline to Month 3.

Partial-onset seizures can be classified into one of the following three groups:

• Simple partial seizures
• Complex partial seizures
• Partial seizures evolving to secondarily generalized seizures.

Of the 520 subjects in the Full Analysis Set (FAS), 449 subjects are included in the analysis of this outcome measure.

FAS comprises all subjects who have been treated with Vimpat® at least once, who fulfill the inclusion criteria and for whom a valid baseline and post-baseline value of seizure frequency is available.

Baseline values for the seizure frequency (SF) during the 12 weeks time period prior to inclusion ('historical baseline'), and the post-baseline values of seizure frequency reported after 6 months were normalized to a 28 days interval.

Change in number of partial-onset seizures was derived as follows:

Change in SF per 28 days = (SF at 6 months per 28 days) - (SF at Baseline per 28 days).

A negative value in change from Baseline means that the value has decreased from Baseline to Month 6.

Partial-onset seizures can be classified into one of the following three groups:

• Simple partial seizures
• Complex partial seizures
• Partial seizures evolving to secondarily generalized seizures.

Of the 520 subjects in the Full Analysis Set (FAS), 500 subjects are included in the analysis of this outcome measure.

FAS comprises all subjects who have been treated with Vimpat® at least once, who fulfill the inclusion criteria and for whom a valid baseline and post-baseline value of seizure frequency is available.

Baseline values for the seizure frequency (SF) during the 12 weeks time period prior to inclusion ('historical baseline'), and the post-baseline values of seizure frequency reported after 3 months were normalized to a 28 days interval.

Change in number of partial-onset seizures with secondary generalization was derived as follows:

Change in SF per 28 days = (SF at 3 months per 28 days) - (SF at Baseline per 28 days).

A negative value in change from Baseline means that the value has decreased from Baseline to Month 3.

Partial-onset seizures with secondary generalization can be classified into one of the following three groups:

• Simple partial seizures evolving to generalized seizures
• Complex partial seizures evolving to generalized seizures
• Simple partial seizures evolving to Complex partial seizures evolving to generalized seizures.

Of the 520 subjects in the Full Analysis Set (FAS), 447 subjects are included in the analysis of this outcome measure.

FAS comprises all subjects who have been treated with Vimpat® at least once, who fulfill the inclusion criteria and for whom a valid baseline and post-baseline value of seizure frequency is available.

Baseline values for the seizure frequency (SF) during the 12 weeks time period prior to inclusion ('historical baseline'), and the post-baseline values of seizure frequency reported after 6 months were normalized to a 28 days interval.

Change in number of partial-onset seizures with secondary generalization was derived as follows:

Change in SF per 28 days = (SF at 6 months per 28 days) - (SF at Baseline per 28 days).

A negative value in change from Baseline means that the value has decreased from Baseline to Month 6.

Partial-onset seizures with secondary generalization can be classified into one of the following three groups:

• Simple partial seizures evolving to generalized seizures
• Complex partial seizures evolving to generalized seizures
• Simple partial seizures evolving to Complex partial seizures evolving to generalized seizures.

Of the 520 subjects in the Full Analysis Set (FAS), 500 subjects are included in the analysis of this outcome measure.

FAS comprises all subjects who have been treated with Vimpat® at least once, who fulfill the inclusion criteria and for whom a valid baseline and post-baseline value of seizure frequency is available.

The number of subjects affected by any Treatment Emergent Adverse Event (TEAE) during the course of the study from Day 0 up to Month 6 is presented below.

All 571 subjects in the Safety Set are included in the analysis of this outcome measure.

Safety Set comprises all patients included who have been treated with Vimpat® at least once.