Evaluation of a Low-fluoride Anticaries Toothpaste

Evaluation of a Low-fluoride Anticaries Toothpaste Containing an Innovative Calcium Technology

The purpose of this trial is to evaluate the anticaries remineralizing potential of a toothpaste containing 500 ppm fluoride plus fTCP technology relative to a commercially available toothpaste via a double-blind cross-over in situ (or intra-oral) clinical model, whereby approved human participants will wear an orthodontic appliance fitted with an enamel specimen for the duration of a leg (28 days). There will be two test legs.

Inclusion Criteria:

• 30 adult subjects (between 18-50 years of age)