Efficacy Study of Lisdexamfetamine to Treat Bipolar Depression

Adjunctive Lisdexamfetamine in Bipolar Depression

The specific aim of this study is to evaluate the efficacy and tolerability of a stimulant (lisdexamfetamine) in the adjunctive treatment of bipolar disorder.

Inclusion Criteria:

• Men and women, through the ages of 18 and 55 years, inclusive.

Exclusion Criteria:

• Women who are pregnant, lactating, or of childbearing potential who are not using adequate contraceptive measures.
• Subjects who are displaying clinically significant homicidality or suicidality
• Clinically unstable medical disease, including cardiovascular, hepatic, renal, gastrointestinal, pulmonary, metabolic, endocrine or other systemic disease. Subjects should be biochemically euthyroid to enter the study.