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| Name | Class |
|---|---|
| McCormick Canada Co | UNKNOWN |
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The general objective of the study is to investigate the effects of the daily consumption of spices and herbs for four (4) consecutive weeks in endothelial function and cardiovascular risk factors of men and postmenopausal women.
The purpose is to assess whether the polyphenol/antioxidant content of different spices will affect endothelial function and other cardiovascular risk factors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dietary supplement: Cinnamon | Experimental |
| |
| Dietary supplement: Oregano | Experimental |
| |
| Dietary supplement: Ginger | Experimental |
| |
| Dietary supplement: Rosemary | Experimental |
| |
| Dietary supplement: Black pepper | Experimental |
| |
| Dietary supplement: Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cinnamon | Dietary Supplement | 2.8g/day of cinnamon in capsules during 4 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Endothelial function measured by endopat system (the endothelium-mediated changes in vacular tone) | at week 0 and week 4 |
| Measure | Description | Time Frame |
|---|---|---|
| Circulating level of plasma lipoproteins-lipids | at week 0 and week 4 | |
| Oxidative stress | at week 0 and week 4 | |
| Endothelial activation and inflammatory markers |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Charles Couillard, Ph.D | Laval University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Richardson Centre of Functional Foods and Nutracuticals | Winnipeg | Manitoba | R3T 6C5 | Canada | ||
| Institute of Nutraceuticals and Functional Foods |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24292639 | Derived | Carnovale V, Paradis ME, Gigleux I, Ramprasath VR, Couture P, Jones PJ, Lamarche B, Couillard C. Correlates of reactive hyperemic index in men and postmenopausal women. Vasc Med. 2013 Dec;18(6):340-6. doi: 10.1177/1358863X13507975. |
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| ID | Term |
|---|---|
| C000713927 | ginger extract |
| C000723805 | black pepper oil |
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| Oregano | Dietary Supplement | 2.8g/day of oregano in capsules during 4 weeks. |
|
| Ginger | Dietary Supplement | 2.8g/day of ginger in capsules during 4 weeks. |
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| Rosemary | Dietary Supplement | 2.8g/day of rosemary in capsules during 4 weeks. |
|
| Black pepper | Dietary Supplement | 2.8g/day of black pepper in capsules for 4 weeks. |
|
| Placebo | Dietary Supplement | 2.8 g/day of placebo in capsules (corn starch) during 4 weeks. |
|
| at week 0 and week 4 |
| Québec |
| Quebec |
| G1V 0A6 |
| Canada |