Med Diet Prevention Metabolic Syndrome Men Undergoing Androgen Deprivation Therapy Prostate Cancer

Eight Week Plant-based Mediterranean Diet as Prevention of Metabolic Syndrome in Men Undergoing Androgen Deprivation Therapy for Prostate Cancer: A BrUOG Pilot Study

The purpose of this study is to assess for changes in a patient's overall energy level and well-being (quality of life) after 8 weeks of dietary intervention.

Primary Objective: To assess for changes in the following measurements after 8 weeks of following a Mediterranean diet-- LDL, HDL, TG, FBS, creatinine, serum testosterone, triglycerides, serum insulin, CRP, 1bs, Waist circumference, blood pressure, body weight

Inclusion Criteria:

• Histologically documented carcinoma of the prostate
• On treatment with androgen deprivation therapy for at least 3 months
• Required laboratory values:
• Serum creatinine less than 2.5
• Triglycerides <300
• Fasting glucose < 126
• Testosterone level <50

Exclusion Criteria:

• No diabetes mellitus (Type 1 or 2)
• No renal failure (Serum creatinine > 2.5)
• No active cardiac disease -no history of myocardial infarction/stroke within the last 12 months, no recurrent unstable angina, uncontrolled/unstable arrhythmias, uncontrolled hypertension (systolic blood pressure >160, diastolic blood pressure >100)
• No severe peripheral vascular disease
• No commencement of lipid lowering agent within 8 weeks of enrollment the study or change in dose throughout the study