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| Name | Class |
|---|---|
| Abbott Japan Co.,Ltd | INDUSTRY |
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The purpose of this study is to assess the safety, tolerability, and pharmacokinetics of blinded, single ascending oral doses of ABT 072 under non-fasting conditions in healthy adult Japanese male subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ABT-072 Tablet | Active Comparator | ABT-072 50 mg Tablet, every day (QD), single ascending doses, groups 1-3 |
|
| Placebo | Placebo Comparator | Placebo Tablet, QD, single doses, groups 1-3 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ABT-072 | Drug | See arm description for more information |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Safety and tolerability assessment | Safety and tolerability assessment by the evaluation of vital signs, ECGs, physical exams, clinical lab testing and adverse event monitoring. | Day 1 to Day 4 and Day 15. |
| Pharmacokinetic profile evaluation | Single Dose Pharmacokinetic profile evaluation | Day 1 to Day 4 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kazuko Kobayashi | Abbott Japan Co.,Ltd | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kagoshima | Prefecture | Japan |
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| ID | Term |
|---|---|
| D006526 | Hepatitis C |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D006525 | Hepatitis, Viral, Human |
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| ID | Term |
|---|---|
| C000625346 | ABT-072 |
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| Placebo |
| Drug |
See arm description for more information |
|
| D014777 |
| Virus Diseases |
| D018178 | Flaviviridae Infections |
| D012327 | RNA Virus Infections |
| D006505 | Hepatitis |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |