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Alcohol abuse is associated with a variety of clinical diseases, but studies on prevalence of different somatic diseases among alcohol abusers are lacking. Studies on populations in an out-day patients' clinic are also lacking.
The investigators aim to study somatic health standard in an out-day patients' clinic population of alcohol abusers, with regard to prevalence of different kinds of somatic diseases, and how the interaction of somatic and psychiatric treatment can influence on patients quality of life. Clinical examination including blood samples and echocardiographic examinations in all participants, other additional examinations (as x-ray, CT or MRI if indicated by clinical findings).
Retrospective methods will be used to study former somatic disease, cross-section design to study present somatic disease and prospective design to study quality of life, psychiatric and somatic health after combination of psychiatric and somatic examinations and treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Out-day patients' clinic | Alcohol abusers referred to out-day patients' clinic which consent to participate in the study |
| |
| Control | Control group for the cardiac arm of the study will be matched controls from the Nord-Trøndelag Health Study (HUNT) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Psychiatric and somatic examinations and ,if clinical indicated, treatment | Other | Patients referred to the clinic will be given optimal treatment for revealed psychiatric and/or somatic disease including conversational therapy, and if indicated therapeutic interventions with respect to any kind of disease. |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of different kinds of somatic disease | Prevalence of somatic disease at study attendance of any kind, specified for heart disease, gall- and liver disease, neuropathic disease. | 3 months after inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of former somatic disease | Prevalence of former somatic disease investigated by anamnestic examination, search in patient journals and communication with the patients community health service. | 3 months after inclusion |
| Outcome of psychiatric and somatic treatment of alcohol abusers |
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Inclusion Criteria:
Exclusion Criteria:
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Alcohol abusers referred to the out-day patients' clinic at Dep. of Psychiatry, Levanger Hospital, Norway
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| Name | Affiliation | Role |
|---|---|---|
| Erling Dalen, MD | Helse Nord-Trøndelag HF | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Levanger Hospital, Dep. of Psychiatry | Levanger | N-7600 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12626999 | Background | Moss M, Parsons PE, Steinberg KP, Hudson LD, Guidot DM, Burnham EL, Eaton S, Cotsonis GA. Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock. Crit Care Med. 2003 Mar;31(3):869-77. doi: 10.1097/01.CCM.0000055389.64497.11. | |
| 20109599 |
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| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D017093 | Liver Failure |
| D003866 | Depressive Disorder |
| D020269 | Alcoholic Neuropathy |
| D006333 | Heart Failure |
| D003863 | Depression |
| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
| D048550 | Hepatic Insufficiency |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D011570 | Psychiatry |
| D013812 | Therapeutics |
| ID | Term |
|---|---|
| D001525 | Behavioral Sciences |
| D004191 | Behavioral Disciplines and Activities |
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Conventional blood samples including i.e. glycosylated haemoglobin, serum ferritin, serum gamma-GT, B-type natriuretic peptide.
|
Quality of life and score of somatic and psychiatric health 1 year after inclusion |
| 1 year after stopped inclusion |
| Awtry EH, Philippides GJ. Alcoholic and cocaine-associated cardiomyopathies. Prog Cardiovasc Dis. 2010 Jan-Feb;52(4):289-99. doi: 10.1016/j.pcad.2009.11.004. |
| 17189035 | Background | Moss M, Burnham EL. Alcohol abuse in the critically ill patient. Lancet. 2006 Dec 23;368(9554):2231-42. doi: 10.1016/S0140-6736(06)69490-7. |
| 25625990 | Derived | Dalen E, Holmen J, Nordahl HM. Somatic health of patients at an outpatient clinic for substance abuse. Tidsskr Nor Laegeforen. 2015 Jan 27;135(2):127-31. doi: 10.4045/tidsskr.13.0801. eCollection 2015 Jan 27. English, Norwegian. |
| D019964 |
| Mood Disorders |
| D001523 | Mental Disorders |
| D011115 | Polyneuropathies |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D020268 | Alcohol-Induced Disorders, Nervous System |
| D020258 | Neurotoxicity Syndromes |
| D011041 | Poisoning |
| D064419 | Chemically-Induced Disorders |
| D020751 | Alcohol-Induced Disorders |
| D019973 | Alcohol-Related Disorders |
| D019966 | Substance-Related Disorders |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |