Hospitalization or Ambulatory Treatment of Acute Diverticulitis

Randomized Trial Comparing Two Treatment Strategies for Acute Diverticulitis. Hospitalization or Ambulatory Antibiotic Treatment

The purpose of 01DIVER is to evaluate efficacy and safety of a home treatment protocol for non complicated diverticulitis compared with management in the hospital. The hypothesis is that a ambulatory treatment with oral antibiotic and progressive introduction of diet is not inferior to the conservative management in hospital in patients with acute not complicated sigmoid diverticulitis, shown by contrast enhanced CT scan. Patients are prospectively randomized to conservative antibiotic treatment either to ambulatory or to hospital treatment.

Inclusion Criteria:

• Age older than 18 years
• Diagnosis of mild diverticulitis by abdominal computerized tomography
• Signed informed consent

Exclusion Criteria:

• Severe diverticulitis
• Informed consent not signed
• Suspicion of colon cancer
• Pneumoperitoneum
• Intolerance for oral feeding
• Antibiotics for diverticulitis in the last month
• Immunosuppression
• Pregnancy or lactation
• Severe (decompensated) other illness
• Psychological or social problems