Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-708163

Randomized, Placebo-controlled, Double-blind, Single- and Multiple-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-708163 in Healthy Young Male and Elderly Male and Female Chinese Subjects

The purpose of the study is to evaluate the pharmacokinetics, safety and tolerability of BMS-708163 administered as single and multiple doses in Chinese subjects

Inclusion Criteria:

• Healthy male subjects 18-45 yrs old and 65 yrs or older inclusive and postmenopausal female 65 yrs or older

Exclusion Criteria:

• Women of childbearing potential
• Gastrointestinal disorders
• Bleeding disorders
• Peptic ulcer disease
• Abnormal ECG
• Abnormal Clinical laboratory tests
• Abnormal Thyroid
• Congestive heart failure
• Cholecystectomy
• Asthma
• Hypertension
• Inability to tolerate oral medication
• Inability to be venipunctured and/or tolerate venous access