Contrast Enhanced Ultrasonography (CEUS) of Patients With Crohn's Disease

High Frequency Ultrasound and Contrast Enhanced Ultrasound of Patients Treated for Deterioration of Crohn's Disease

The purpose of this study is investigate if high frequency sonography and contrast enhanced sonography can be used to predict remission in patients with deterioration of Crohn's disease treated with steroids or tumor necrosis factor (TNF) alfa inhibitors.

Inclusion Criteria:

• Deterioration of Crohn's disease
• CDAI>150
• Treated with systemic steroids or TNF alfa inhibitors
• Lesion found on ultrasound

Exclusion Criteria:

• Disease location not reachable with ileocolonoscopy
• Pregnancy
• Acute coronary disease
• Unstable coronary disease
• Previous allergic reaction to SonoVue or its components