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This study will evaluate the immunogenicity of rabies vaccine at 13 months, 3 year and 5 years after initial vaccination, administered in two different post-exposure vaccination schedules
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Arm 1 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No vaccine administered; subjects only have blood sampling for immunogenicity | Other | No vaccine administered; subjects only have blood sampling for |
|
| Measure | Description | Time Frame |
|---|---|---|
| Rabies virus neutralizing antibody(RVNA) responses 13months, 3 years and 5 years after completion of initial vaccination series as evaluated by percentage of subjects with RVNA greater than or equal to 0.5 IU/mL | 13 months, 3 years and 5 years after initial vaccination |
| Measure | Description | Time Frame |
|---|---|---|
| Rabies virus neutralizing antibody(RVNA) responses 13months, 3 years and 5 years after completion of initial vaccination series as evaluated by geometric mean concentration | 13months, 3 years and 5years after initial vaccination |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects who received complete vaccine series in accordance to the designated vaccination schedule in the previous M49P8 study
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jizhou County | Hebei | 053200 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25483635 | Derived | Ma J, Wang H, Li J, Chang L, Xie Y, Liu Z, Zhao Y, Malerczyk C. A randomized open-labeled study to demonstrate the non-inferiority of purified chick-embryo cell rabies vaccine administered in the Zagreb regimen (2-1-1) compared with the Essen regimen in Chinese adults. Hum Vaccin Immunother. 2014;10(10):2805-12. doi: 10.4161/21645515.2014.972773. |
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| ID | Term |
|---|---|
| D011818 | Rabies |
| ID | Term |
|---|---|
| D018353 | Rhabdoviridae Infections |
| D018701 | Mononegavirales Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D007239 | Infections |
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