It is believed that probiotic Lactobacillus reuteri will improve the symptoms of breast-fed infants with colic.

Inclusion Criteria:

• Ifants aged between 14 and 60 days
• Breast fed, exclusively during length of trial
• Diagnosis of infantile colic according to Wessel's criteria i.e paroxysmal fussing in infancy for more than three hours per day, at least three days per week.
• Debut of colic symptoms 6+/-1 days before randomization
• Gestational age between 37 and 42 weeks
• Apgar score higher than 7 at 5 minutes
• Mothers willing to follow a cows mild-free diet (free from mild, yoghurt, cheese etc) during the study period
• Written informed consent from one or both parents
• Stated availability throughout the study period

Exclusion Criteria:

• Major chronic disease
• Gastrointestinal disease but controlled GERD with or without medication is not an exclusion criteria
• Administration of anitbiotics the week before randomization
• Administration of probiotics the week before randomization
• Participation in other clinical trials