Safety and Efficacy Study of a New Antiviral Drug to Prev... | NCT01063829

Status Module

Name	Class
Quintiles, Inc.	INDUSTRY

Oversight Module

Design Module

Interventional Study Design

Biospecimen

No data available

No data is available for this block.

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Dose regimen 1	Experimental	60 mg AIC246, one tablet per day	Drug: 60 mg AIC246
Dose regimen 2	Experimental	120 mg AIC246, one tablet per day	Drug: 120 mg AIC246
Dose regimen 3	Experimental	240 mg AIC246, one tablet per day	Drug: 240 mg AIC246
Placebo	Other	Placebo arm	Other: Placebo

Name	Type	Description	Arm Group Labels	Other Names
60 mg AIC246	Drug	Oral administration	Dose regimen 1
120 mg AIC246

Measure	Description	Time Frame
Number of Participants With "HCMV Prophylaxis Failure"		84 days
Time to Onset of "HCMV Prophylaxis Failure"		84 days

Measure	Description	Time Frame
Number of Patients With Systemic Detectable HCMV Replication.		84 days

Eligibility Module

Facility	Status	City	State	ZIP	Country	Contacts
UCLA Medical Center		Los Angeles	California		United States
Stanford University Hospital

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
24806159	Derived	Chemaly RF, Ullmann AJ, Stoelben S, Richard MP, Bornhauser M, Groth C, Einsele H, Silverman M, Mullane KM, Brown J, Nowak H, Kolling K, Stobernack HP, Lischka P, Zimmermann H, Rubsamen-Schaeff H, Champlin RE, Ehninger G; AIC246 Study Team. Letermovir for cytomegalovirus prophylaxis in hematopoietic-cell transplantation. N Engl J Med. 2014 May 8;370(19):1781-9. doi: 10.1056/NEJMoa1309533.

Results Section

Participant Flow Module

ID	Title	Description
FG000	AIC246 (60 mg)	AIC246: Oral Administration
FG001	AIC246 (120 mg)	AIC246: Oral Administration

Baseline Characteristics Module

Outcome Measures Module

Adverse Events Module

More Info Module

Arm/Group Information

ID	Title	Description
BG000	AIC246 (60 mg)	AIC246: Oral Administration
BG001	AIC246 (120 mg)	AIC246: Oral Administration
BG002	AIC246 (240 mg)	AIC246: Oral Administration
BG003	Placebo	Placebo: Oral Administration
BG004	Total	Total of all reporting groups

Baseline Measures

Title

Description

Population Description

Parameter Type

Dispersion Type

Unit of Measure

Calculate Percentage

Denominator Units Selected

Denominators

Classes

Age, Continuous

Mean

Standard Deviation

years

Title

Denominators

Categories

Title	Measurements
	BG00050.5± 13.03 BG00151.6± 12.79 BG00250.7± 11.78 BG003

Sex: Female, Male

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
Female	BG00019 BG0019 BG002

Region of Enrollment

Number

participants

Title

Denominators

Categories

United States

Title	Measurements
	BG00018 BG00119 BG002

Type

Title

Description

Population Description

Reporting Status

Anticipated Posting Date

Parameter Type

Dispersion Type

Unit of Measure

Calculate Percentage

Time Frame

Units Analyzed

Denominator Units Selected

Arm/Group Information

Denominators

Classes

Analyses

Primary

Number of Participants With "HCMV Prophylaxis Failure"

Posted

Count of Participants

Participants

84 days

ID	Title	Description
OG000	AIC246 (60 mg)	AIC246: Oral Administration
OG001	AIC246 (120 mg)	AIC246: Oral Administration
OG002	AIC246 (240 mg)	AIC246: Oral Administration
OG003	Placebo	Placebo: Oral Administration

Units	Counts
Participants	OG00033 OG00131 OG00234 OG003

Title

Denominators

Categories

Title	Measurements
	OG00016 OG00110 OG00210 OG003

Group IDs	Group Description	Statistical Method	Statistical Comment	P-Value	P-Value Comment	Parameter Type	Parameter Value	Dispersion Type	Dispersion Value	Confidence Interval Sides	Confidence Interval %	CI Lower Limit	CI Upper Limit	CI Lower Limit Comment	CI Upper Limit Comment	Estimate Comment	Tested Non-Inferiority	Non-Inferiority Type	Non-Inferiority Comment	Other Analysis Description
OG002 OG003		Fisher Exact		0.007														Superiority or Other
OG001 OG003		Fisher Exact		0.014

Primary

Time to Onset of "HCMV Prophylaxis Failure"

Posted

Number

days

84 days

ID	Title	Description
OG000	AIC246 (60 mg)	AIC246: Oral Administration
OG001	AIC246 (120 mg)	AIC246: Oral Administration
OG002	AIC246 (240 mg)	AIC246: Oral Administration
OG003	Placebo	Placebo: Oral Administration

Units	Counts
Participants	OG000

Secondary

Number of Patients With Systemic Detectable HCMV Replication.

Posted

Count of Participants

Participants

84 days

ID	Title	Description
OG000	AIC246 (60 mg)	AIC246: Oral Administration
OG001	AIC246 (120 mg)	AIC246: Oral Administration
OG002	AIC246 (240 mg)	AIC246: Oral Administration
OG003	Placebo	Placebo: Oral Administration

Units	Counts
Participants	OG000

Arm/Groups

ID	Title	Description	Deaths (Affected)	Deaths (At Risk)	Serious Events (Affected)	Serious Events (At Risk)	Other Events (Affected)	Other Events (At Risk)
EG000	AIC246 (60 mg)	AIC246: Oral Administration	2	33	13	33	31	33
EG001	AIC246 (120 mg)	AIC246: Oral Administration	1	31	15	31	29	31
EG002	AIC246 (240 mg)	AIC246: Oral Administration	1	34	12	34	34	34
EG003	Placebo	Placebo: Oral Administration	1	33	16	33	33	33

Serious Adverse Events

Term	Organ System	Statistical Information
Pneumonia	Infections and infestations	EG0002 events2 affected33 at risk EG0012 events2 affected31 at risk EG0022 events2 affected34 at risk EG0030 events0 affected33 at risk
Epstein-Barr Virus Infestcion	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Cytomegalovirus Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0012 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Alcaligenes Infection	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Bacteraemia	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Clostridial Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Enterococcal Bacteraemia	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Human Herpesvirus 6 Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Oral Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Pneumonia Primary Atypical	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Pneumonia Respiratory Syncytial Viral	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Sepsis	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Septic Shock	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Device Related Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Enterobacter Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Herpes Virus Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pneumonia Bacterial	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Upper Respiratory Tract Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Myeloid Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Leukaemia Recurrent	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Lymphoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Acute Lymphocytic Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Diffuse Large B-Cell Lymphoma Recurrent	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Myelodysplastic Syndrome	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Myeloid Leukaemia (in Remission)	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Non-Hodgkin's Lymphoma Recurrent	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Graft Versus Host Disease in Intestine	Immune system disorders	EG0004 events4 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Acute Graft Versus Host Disease in Liver	Immune system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Graft Versus Host Disease	Immune system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Graft Versus Host Disease in Skin	Immune system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Dehydration	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Diabetic Ketoacidosis	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hyperkalaemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypoglykaemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hyponatraemia	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Thrombocytopenia	Blood and lymphatic system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Febrile Neutropenia	Blood and lymphatic system disorders	EG0000 events0 affected33 at risk EG0012 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Anaemia	Blood and lymphatic system disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Spinal Compression Fracture	Injury, poisoning and procedural complications	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Transplant Failure	Injury, poisoning and procedural complications	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Anginga Pectoris	Cardiac disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Atrial Fibrillation	Cardiac disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pericarditis	Cardiac disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Diarrhoea	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Gastritis	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Vomitting	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Nausea	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
General Physical Health Deterioration	General disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Generalised Oedema	General disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pyrexia	General disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hepatic Enzyme Increased	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Liver Function Test	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Staphylococcus Test Positive	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Loss of Consciousness	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Paraesthesia	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Syncope	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Convulsion	Nervous system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Back Pain	Musculoskeletal and connective tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Flank Pain	Musculoskeletal and connective tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Respiratory Failure	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pulmonary Embolism	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Venoocclusive Liver Disease	Hepatobiliary disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Renal Failure	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003

Other Adverse Events

Term	Organ System	Statistical Information
Diarrhoea	Gastrointestinal disorders	EG00011 events9 affected33 at risk EG00111 events9 affected31 at risk EG00214 events11 affected34 at risk EG00313 events10 affected33 at risk
Nausea	Gastrointestinal disorders	EG0008 events7 affected33 at risk EG00116 events8 affected31 at risk EG0027 events7 affected34 at risk EG003
Vomitting	Gastrointestinal disorders	EG0004 events4 affected33 at risk EG00111 events10 affected31 at risk EG0028 events8 affected34 at risk EG003
Constipation	Gastrointestinal disorders	EG0005 events4 affected33 at risk EG0013 events3 affected31 at risk EG0023 events3 affected34 at risk EG003
Abdominal Pain	Gastrointestinal disorders	EG0003 events3 affected33 at risk EG0013 events3 affected31 at risk EG0023 events3 affected34 at risk EG003
Dyspepsia	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0013 events2 affected31 at risk EG0024 events4 affected34 at risk EG003
Abdominal Pain Upper	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0024 events4 affected34 at risk EG003
Abdominal Distension	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0023 events2 affected34 at risk EG003
Abdominal Discomfort	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0022 events2 affected34 at risk EG003
Dry Mouth	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Flatulence	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Proctalgia	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Dysphagia	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Gastrooesophageal Reflux Disease	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Stomatitis	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Anorectal Discomfort	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Ascites	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Breath Odour	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Colitis	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Colitis Ischaemic	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Gastritis	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Gastrointestinal Haemorrhage	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Haemorrhoids	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Lip Dry	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Lip Swelling	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Lip Ulceration	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Oral Discomfort	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Swollen Tongue	Gastrointestinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Gingivitis	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Oral Pain	Gastrointestinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Cytomegalovirus Infection	Infections and infestations	EG0006 events6 affected33 at risk EG0016 events6 affected31 at risk EG0025 events5 affected34 at risk EG003
Candidiasis	Infections and infestations	EG0004 events4 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Pneumonia	Infections and infestations	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0023 events3 affected34 at risk EG003
Upper Respiratory Tract Infection	Infections and infestations	EG0002 events2 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Nasopharyngitis	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0024 events4 affected34 at risk EG003
Urinary Tract Infection	Infections and infestations	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0022 events2 affected34 at risk EG003
Eppstein-Barr Virus Infection	Infections and infestations	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Pseudomonas Infection	Infections and infestations	EG0002 events2 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Sinusitis	Infections and infestations	EG0000 events0 affected33 at risk EG0013 events3 affected31 at risk EG0020 events0 affected34 at risk EG003
Bacteraemia	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Folliculitis	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Oral Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Respiratory Tract Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Staphylococcal Infection	Infections and infestations	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Urinary Tract Infection Enterococcal	Infections and infestations	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Eppstein-Barr Viraemia	Infections and infestations	EG0002 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Rhinitis	Infections and infestations	EG0000 events0 affected33 at risk EG0012 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Alcaligenes Infection	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Bacterial Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
BK Virus Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Body Tinea	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Bronchitis	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Cellulitis	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Clostridial Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Cystitis Viral	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Enterococcal Bacteraemia	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Herpes Simplex	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Human Herpesvirus 6 Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Klebsiella Bacteraemia	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Micrococcus Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Oesphageal Candidiasis	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Oral Candidiasis	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Oral Herpes	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Parainfluenzae Virus Infection	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pharyngitis	Infections and infestations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pneumonia Herpes Viral	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Pneumonia Primary Atypical	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Pneumonia Respiratory Syncytial Viral	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Septic Shock	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Staphylococcal Bacteraemia	Infections and infestations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Stenotrophomonas Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Adenovirus Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Cytomegalovirus Viraemia	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Device Related Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Enterobacter Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Fungal Skin Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Herpes Virus Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Paronychia	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Parotitis	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pneumonia Bacterial	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Skin Infection	Infections and infestations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Rash	Skin and subcutaneous tissue disorders	EG0005 events4 affected33 at risk EG0017 events5 affected31 at risk EG0026 events4 affected34 at risk EG003
Puritus	Skin and subcutaneous tissue disorders	EG0002 events2 affected33 at risk EG0014 events4 affected31 at risk EG0025 events5 affected34 at risk EG003
Erythema	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0015 events4 affected31 at risk EG0028 events4 affected34 at risk EG003
Dry Skin	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0013 events3 affected31 at risk EG0021 events1 affected34 at risk EG003
Rash Erythematous	Skin and subcutaneous tissue disorders	EG0002 events1 affected33 at risk EG0010 events0 affected31 at risk EG0022 events1 affected34 at risk EG003
Petechiae	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0023 events2 affected34 at risk EG003
Hyperhidrosis	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Night Sweats	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Rash Pruritic	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Skin Hyperpigmentation	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Actinic Keratosis	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Febrile Neutrophilic Dermatosis	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Alopecia	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Blood Blister	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Decubitus Ulcer	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Dermal Cyst	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Dermatitis	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Dermatitis Contact	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypoaesthesia Facial	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Lichenfication	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Nail Disorder	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Palmar Eythema	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Perivascular Dermatitis	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Pruritis Generalised	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Rash Maculo-Papular	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Rash Morbilliform	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Rash Papular	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Skin Discolouration	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Skin Exfoliation	Skin and subcutaneous tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Skin Ulcer	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Ecchymosis	Skin and subcutaneous tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Fatigue	General disorders	EG0006 events3 affected33 at risk EG0019 events8 affected31 at risk EG0026 events4 affected34 at risk EG003
Oedema Peripheral	General disorders	EG0004 events4 affected33 at risk EG0013 events3 affected31 at risk EG0028 events8 affected34 at risk EG003
Pyrexia	General disorders	EG0003 events3 affected33 at risk EG0014 events4 affected31 at risk EG0025 events5 affected34 at risk EG003
Oedema	General disorders	EG0001 events1 affected33 at risk EG0013 events3 affected31 at risk EG0022 events2 affected34 at risk EG003
Chills	General disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Asthenia	General disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Catheter Site Erythema	General disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Catheter Site Pain	General disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Chest Pain	General disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Face Oedema	General disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Local Swelling	General disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Malaise	General disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Non-Cardiac Chest Pain	General disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Application Site Hypersensitivity	General disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Axillary Pain	General disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Gait Distrubance	General disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Decreased Appetite	Metabolism and nutrition disorders	EG0004 events4 affected33 at risk EG0012 events2 affected31 at risk EG0025 events5 affected34 at risk EG003
Hyperkalaemia	Metabolism and nutrition disorders	EG0004 events4 affected33 at risk EG0012 events2 affected31 at risk EG0022 events2 affected34 at risk EG003
Dehydration	Metabolism and nutrition disorders	EG0003 events3 affected33 at risk EG0013 events3 affected31 at risk EG0021 events1 affected34 at risk EG003
Hypokalaemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0013 events3 affected31 at risk EG0022 events2 affected34 at risk EG003
Hyperglycaemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0013 events3 affected31 at risk EG0021 events1 affected34 at risk EG003
Diabetes Mellitus	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypomagnesaemia	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Diabetic Ketoacidosis	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Electrolyte Imbalance	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Fluid Overload	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Fluid Retention	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Food Intolerance	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Haemosiderosis	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Hyperphosphataemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypocalcaemia	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypoglycaemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hyponatraemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypoproteinaemia	Metabolism and nutrition disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hyperuricaemia	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Vitamin D Deficiency	Metabolism and nutrition disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Cough	Respiratory, thoracic and mediastinal disorders	EG0002 events2 affected33 at risk EG00111 events8 affected31 at risk EG0025 events5 affected34 at risk EG003
Oropharyngeal Pain	Respiratory, thoracic and mediastinal disorders	EG0003 events2 affected33 at risk EG0013 events3 affected31 at risk EG0021 events1 affected34 at risk EG003
Dyspnoea	Respiratory, thoracic and mediastinal disorders	EG0002 events2 affected33 at risk EG0011 events1 affected31 at risk EG0023 events3 affected34 at risk EG003
Rhinorrhoea	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0023 events3 affected34 at risk EG003
Lung Infiltration	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Epistaxis	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Nasal Congestion	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Postnasal Drip	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Pulmonary Ebolism	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Throat Irritation	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Bronchial Obstruction	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Dysphonia	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Dyspnoea Exertional	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Emphysema	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypoxia	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Lung Disorder	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Painful Respiration	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Pharyngeal Erythema	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Pleural Effusion	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Pleurisy	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Productive Cough	Respiratory, thoracic and mediastinal disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Respiratory Disorder	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Sinus Congestion	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Choking	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Chronic Obstructive Pulmonary Disease	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pulmonary Congestion	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pulmonary Oedema	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Rhinitis Allergic	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Sleep Apnoea Syndrome	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Wheezing	Respiratory, thoracic and mediastinal disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Headache	Nervous system disorders	EG0004 events4 affected33 at risk EG0013 events3 affected31 at risk EG0028 events8 affected34 at risk EG003
Neuropathy Peripheral	Nervous system disorders	EG0003 events3 affected33 at risk EG0013 events3 affected31 at risk EG0021 events1 affected34 at risk EG003
Tremor	Nervous system disorders	EG0001 events1 affected33 at risk EG0013 events3 affected31 at risk EG0020 events0 affected34 at risk EG003
Dizziness	Nervous system disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Dysgeusia	Nervous system disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Paraesthesia	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Polyneuropathy	Nervous system disorders	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Somnolence	Nervous system disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Burning Sensation	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypoaestesia	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Loss of Consciousness	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Neuralgia	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Nystagmus	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Restless Leg Syndrome	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Sinus Headache	Nervous system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Syncope	Nervous system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Ageusia	Nervous system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Balance Disorder	Nervous system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Convulsion	Nervous system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
VIIth Nerve Paralysis	Nervous system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Back Pain	Musculoskeletal and connective tissue disorders	EG0002 events2 affected33 at risk EG0014 events4 affected31 at risk EG0023 events2 affected34 at risk EG003
Muscles Spasms	Musculoskeletal and connective tissue disorders	EG0002 events1 affected33 at risk EG0012 events2 affected31 at risk EG0026 events4 affected34 at risk EG003
Bone Pain	Musculoskeletal and connective tissue disorders	EG0002 events2 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Myalgia	Musculoskeletal and connective tissue disorders	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0022 events2 affected34 at risk EG003
Arthralgia	Musculoskeletal and connective tissue disorders	EG0003 events2 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Musculoskeletal Pain	Musculoskeletal and connective tissue disorders	EG0003 events2 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Pain in Extremity	Musculoskeletal and connective tissue disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Muscular Weakness	Musculoskeletal and connective tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Myopathy	Musculoskeletal and connective tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Arthrophathy	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0012 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Chest Wall Mass	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Exostosis	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Muscle Atrophy	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Musculoskeletal Stiffness	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Osteonecrosis	Musculoskeletal and connective tissue disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Osteoporosis	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Musculoskeletal Chest Pain	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Myosclerosis	Musculoskeletal and connective tissue disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hepatic Enzyme Increased	Investigations	EG0002 events2 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Blood Creatinine Increased	Investigations	EG0001 events1 affected33 at risk EG0013 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Alanine Aminotransferase Increased	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0023 events2 affected34 at risk EG003
Aspartate Aminotransferase Increased	Investigations	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Blood Alkaline Phosphatase Increased	Investigations	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Blood Folate Decreased	Investigations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Blood Urea Increased	Investigations	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Red Blood Cell Morphology Abnormal	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Transaminases Increased	Investigations	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Weight Decreased	Investigations	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Blood Creatine Increased	Investigations	EG0000 events0 affected33 at risk EG0012 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Liver Function Test	Investigations	EG0002 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Antithrombin III Decreased	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Aspergillus Test Positive	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Blood Amylase Increased	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Blood Fibrinogen Decreased	Investigations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Blood Potassium Increased	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Blood Testosterone Decreased	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
C-Reactive Protein Increased	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Computerised Tomogram Abnormal	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Cytomegalovirus Test Positive	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Electrocardiogram QT Prolonged	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Electrocardiogram ST Segment Elevation	Investigations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Epstein-Barr Virus Test Positive	Investigations	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Gamma-Glutamyltransferase Increased	Investigations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Lipase Increased	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Polyomavirus Test Positive	Investigations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Weight Increased	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
White Blood Cell Count Decreased	Investigations	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Staphylococcus Test Positive	Investigations	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Graft Versus Host Disease	Immune system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Renal Failure	Renal and urinary disorders	EG0005 events5 affected33 at risk EG0015 events5 affected31 at risk EG0023 events3 affected34 at risk EG003
Nocturia	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0023 events3 affected34 at risk EG003
Dysuria	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0022 events2 affected34 at risk EG003
Micturition Urgency	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Haematuria	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Inconinence	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Pyuria	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Renal Failure Acute	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Bladder Spasm	Renal and urinary disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Dry Eye	Eye disorders	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0025 events5 affected34 at risk EG003
Conjunctivitis	Eye disorders	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Vision Blurred	Eye disorders	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Cataract	Eye disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0022 events2 affected34 at risk EG003
Eye Irritation	Eye disorders	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Lacrimation Increased	Eye disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0022 events2 affected34 at risk EG003
Conjuctival Hyperaemia	Eye disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Eylid Oedema	Eye disorders	EG0002 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Eye Discharge	Eye disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Eye Pruritus	Eye disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Acute Graft Versus Host Disease in Skin	Immune system disorders	EG0004 events3 affected33 at risk EG0017 events5 affected31 at risk EG0027 events6 affected34 at risk EG003
Acute Graft Versus Host Disease in Intestine	Immune system disorders	EG0003 events3 affected33 at risk EG0010 events0 affected31 at risk EG0026 events5 affected34 at risk EG003
Graft Versus Host Disease	Immune system disorders	EG0001 events1 affected33 at risk EG0013 events2 affected31 at risk EG0022 events2 affected34 at risk EG003
Acute Graft Versus Host Disease in Liver	Immune system disorders	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Drug Hypersensitivity	Immune system disorders	EG0002 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Chronic Graft Versus Host Disease	Immune system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Seasonal Allergy	Immune system disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Ocular Discomfort	Eye disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Sicca Syndrome	Eye disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Visual Impairment	Eye disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Lagophthalmos	Eye disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Anaemia	Blood and lymphatic system disorders	EG0005 events3 affected33 at risk EG0012 events2 affected31 at risk EG0024 events4 affected34 at risk EG003
Neutropenia	Blood and lymphatic system disorders	EG0002 events2 affected33 at risk EG0012 events2 affected31 at risk EG0023 events3 affected34 at risk EG003
Thrombocytopenia	Blood and lymphatic system disorders	EG0002 events2 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Splenomegaly	Blood and lymphatic system disorders	EG0001 events1 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Eosinophilia	Blood and lymphatic system disorders	EG0002 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Monocytosis	Blood and lymphatic system disorders	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Pancytopenia	Blood and lymphatic system disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Febrile Neutropenia	Blood and lymphatic system disorders	EG0000 events0 affected33 at risk EG0012 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Coagulopathy	Blood and lymphatic system disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Lymphopenia	Blood and lymphatic system disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Lymph Node Pain	Blood and lymphatic system disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Insomnia	Psychiatric disorders	EG0005 events5 affected33 at risk EG0014 events4 affected31 at risk EG0022 events2 affected34 at risk EG003
Depression	Psychiatric disorders	EG0003 events3 affected33 at risk EG0012 events2 affected31 at risk EG0020 events0 affected34 at risk EG003
Anxiety	Psychiatric disorders	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Psychotic Disorder	Psychiatric disorders	EG0000 events0 affected33 at risk EG0012 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Decreased Activitiy	Psychiatric disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Delirium	Psychiatric disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Mood Swings	Psychiatric disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Panick Attack	Psychiatric disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Stress	Psychiatric disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Adjustment Disorders	Psychiatric disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Fear	Psychiatric disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Libido Decreased	Psychiatric disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Restlessness	Psychiatric disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Skin Laceration	Injury, poisoning and procedural complications	EG0000 events0 affected33 at risk EG0012 events2 affected31 at risk EG0022 events2 affected34 at risk EG003
Contusion	Injury, poisoning and procedural complications	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Fall	Injury, poisoning and procedural complications	EG0002 events2 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Limb Injury	Injury, poisoning and procedural complications	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Procedural Pain	Injury, poisoning and procedural complications	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Scratch	Injury, poisoning and procedural complications	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Spinal Compression Fracture	Injury, poisoning and procedural complications	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Sunburn	Injury, poisoning and procedural complications	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Suture Related Complication	Injury, poisoning and procedural complications	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypotension	Vascular disorders	EG0002 events2 affected33 at risk EG0012 events2 affected31 at risk EG0021 events1 affected34 at risk EG003
Hypertension	Vascular disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0023 events3 affected34 at risk EG003
Circulatory Collapse	Vascular disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Deep Vain Thrombosis	Vascular disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Flushing	Vascular disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Hot Flush	Vascular disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Orthostatic Hypotension	Vascular disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Ischaemia	Vascular disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Varicophlebitis	Vascular disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Acute Myeloid Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0001 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Leukaemia Recurrent	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Myelodysplastic Syndrome	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Acute Lymphocytic Leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Diffuse Large B-Cell Lymphoma Recurrent	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Lymphoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Melanocytic Naevus	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Multiple Myeloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Acute Myeloid Leukaemia (in Remission)	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Epstein-Barr Virus Associated Lymphoproliferative Disorder	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Tachycardia	Cardiac disorders	EG0002 events2 affected33 at risk EG0013 events3 affected31 at risk EG0020 events0 affected34 at risk EG003
Angina Pectoris	Cardiac disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0021 events1 affected34 at risk EG003
Pericardial Effusion	Cardiac disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Pericarditis	Cardiac disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Sinus Arrhythmia	Cardiac disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Vulvovaginal Dryness	Reproductive system and breast disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Vulvovaginal Pruritus	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003
Atropic Vulvovaginitis	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Dyspareunia	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Erectile Dysfunction	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Genital Lesion	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Menorrhagia	Reproductive system and breast disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Scrotal Erythema	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Vaginal Discharge	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Breast Pain	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Breast Swelling	Reproductive system and breast disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Cholelithiasis	Hepatobiliary disorders	EG0002 events1 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Cholestasis	Hepatobiliary disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hyperbilirubinaemia	Hepatobiliary disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Venoocclusive Liver Disease	Hepatobiliary disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Cushingoid	Endocrine disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Hyperparathyroidism	Endocrine disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypothyroidism	Endocrine disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Inappropriate Antidiuretic Hormone Secretion	Endocrine disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Thyroid Disorder	Endocrine disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Auricular Swelling	Ear and labyrinth disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Middle Ear Effusion	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0021 events1 affected34 at risk EG003
Tinnitus	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0011 events1 affected31 at risk EG0020 events0 affected34 at risk EG003
Vertigo	Ear and labyrinth disorders	EG0001 events1 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Dysacusis	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Ear Congestion	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Ear Pain	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hyperacusis	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Hypoacusis	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Inner Ear Inflammation	Ear and labyrinth disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0020 events0 affected34 at risk EG003
Chimerism	Congenital, familial and genetic disorders	EG0000 events0 affected33 at risk EG0010 events0 affected31 at risk EG0022 events2 affected34 at risk EG003