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The real-time visualization of a needle and nerve during an ultrasound-guided nerve block can be challenging. These difficulties may partly explain the systemic complications of local anesthetics under ultrasound. Injection of small amounts of a solution around the anesthetized nerve (hydro-dissection) has been proposed to enhance contrast outlining its borders and also to improve the visualization of the needle tip. The glucose solution 5% solution is interesting because it allows, unlike saline, to maintain the motor response with neurostimulation. The hydro-dissection can be particularly useful when one suspect hypoechoic vessels near the nerve to be anesthetized. Thereby, the nerve well demarcated and separated from the vessels, injection of local anesthetic is performed in the circumferential diffusion space (like a small pocket) without redirecting needle.
The influence of this hydro-dissection on the nerve block efficiency is unknown. The nerve block quality can be improved because the entire anesthetic is injected in contact with the nerve, but it can also be reduced due to the dilution of the local anesthetic by the glucose solution.
In this randomized study, the investigators test the hypothesis that hydro-dissection does not alter the nerve block onset time.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| nerve block | Active Comparator | median nerve block (6 ml lidocaine 1.5 % with adrenalin 1:200000) |
|
| median nerve block after hydro-dissection | Experimental | median nerve block (6 ml lidocaine 1.5 % with adrenalin 1:200000) after hydro-dissection (glucose 5% solution) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| median nerve block | Procedure | median nerve block performed using ultrasound guidance |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Onset time of sensory blockade (light touch test: total loss of sensation at the two distal phalanges of index) | 30 minutes after injection |
| Measure | Description | Time Frame |
|---|---|---|
| Onset time of sensory blockade (cold test at index finger and thenar eminence) | 30 minutes after injection | |
| Onset time (light touch test at thenar eminence) | 30 minutes after injection | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Marc Fischler | Hôpital Foch | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Privé de l'Ouest Parisien | Trappes | 78190 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22745114 | Derived | Dufour E, Donat N, Jaziri S, Kurdi O, Couturier C, Dreyfus JF, Fischler M. Ultrasound-guided perineural circumferential median nerve block with and without prior dextrose 5% hydrodissection: a prospective randomized double-blinded noninferiority trial. Anesth Analg. 2012 Sep;115(3):728-33. doi: 10.1213/ANE.0b013e31825fa37d. Epub 2012 Jun 28. |
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| median nerve block after hydro-dissection |
| Procedure |
median nerve block performed after hydro-dissection (glucose 5% solution), both using ultrasound guidance |
|
| Onset time for motor blockade |
| 30 minutes after injection |
| Success rate (% of patients with total light touch block at index finger within 30 min evaluation period) | 30 minutes after injection |
| Successful surgical anesthesia | 30 minutes after injection |
| Duration of nerve blockade | 12 hours |
| Nerve block complication | one month |
| Duration of the puncture procedure | 30 minutes after the beginning of the procedure |