Safety Study of BMS-770767 in Subjects With Hypercholesterolemia

A Double-blind, Placebo-Controlled, Parallel-Group, Randomized, Multiple-Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Effects of BMS-770767 in Subjects With Primary Hypercholesterolemia

The purpose of this study is to assess the safety, tolerability and pharmacodynamic effects on LDL cholesterol (LDL-C)

Inclusion Criteria:

• Hypercholesterolemia
• Currently taking a stable daily dose of statin therapy
• Serum triglyceride level < 500mg/dl

Exclusion Criteria

• History of myocardial infarction, coronary angioplasty or bypass grafts, valvular disease or repair, unstable angina pectoris, transient ischemic attack, or cerebrovascular accidents within six months prior to entry into the study
• Congestive heart failure
• Diabetes mellitus
• Active liver disease
• Impaired renal function
• Hepatitis C, B and HIV

This list is not inclusive additional information is provided in the protocol