Diagnostic of Infections Following Major Abdominal Surgery and Burn Injury

Impact of Biomarkers for Early Diagnostic of Infections Following Major Abdominal Surgery and Severe Burn Injuries

This study was designed to investigate, if new biomarkers may improve the early diagnostic of infections following major abdominal surgery and severe burn injuries.

Inclusion Criteria:

• patients with major abdominal surgery (e.g. gastrectomy, hemi-/colectomy, resection of sigma or rectum, resection of liver, esophagectomy)
• patients following severe burn injury (burn surface area >= 15%)
• age >= 18 years
• informed consent

Exclusion Criteria:

• no informed consent
• emergency surgery
• immunocompromising diseases (e.g. HIV+, AIDS, Lymphoma or NonHodgkin-Lymphoma, Autoimmune-Diseases)
• pre-existing liver or renal failure
• chronic therapy with corticoids