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One of the most frequently investigated hypothesis of the pathophysiology underlying Seasonal Affective Disorder(SAD) or so called winterdepression is a disturbance of circadian rhythms. Since the circadian system is especially sensitive for the blue portion of the light spectrum, a new light therapy device with more blue light (blue enriched polychromatic light) was tested for its efficacy to treat SAD. In chronobiological terms this light is hypothesized to be more potent in inducing non-visual effects. In the present study fluorescent tubes that emit a high portion of short wavelength light on top of the normal wavelengths are tested for its superiority in treating SAD. This blue-enriched light (colour temperature 17000 ºK) is compared to standard light treatment (5000 º K) in SAD patients., The investigators hypothesise that blue- enriched light improve the therapeutic effects of light treatment leading to a higher response or the same response in a shorter time schedule compared to standard light treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard Light Treatment | Active Comparator | 30 min of Standard bright light treatment (color 5000K) |
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| Blue enriched Light treatment 20 min | Experimental | 20 minutes of Blue enriched light treatment (color 17000K) |
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| Blue enriched light treatment 30 min | Experimental | 30 minutes of Blue enriched light treatment (color 17000K) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Original Energy Light, | Device | 9000 lux, 30 minutes in the morning |
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| Measure | Description | Time Frame |
|---|---|---|
| SIGH SAD depression observer rating | days 1, 8, 15, 22 |
| Measure | Description | Time Frame |
|---|---|---|
| selfrating of depressive mood | once daily during 22 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Y. Meesters, PhD | Department of Psychiatry, University Medical Center Groningen, The Netherlands | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Psychiatry, University Medical Center Groningen | Groningen | 9700RB | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21911257 | Derived | Gordijn MCM, 't Mannetje D, Meesters Y. The effects of blue-enriched light treatment compared to standard light treatment in Seasonal Affective Disorder. J Affect Disord. 2012 Jan;136(1-2):72-80. doi: 10.1016/j.jad.2011.08.016. Epub 2011 Sep 10. |
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| ID | Term |
|---|---|
| D016574 | Seasonal Affective Disorder |
| ID | Term |
|---|---|
| D003866 | Depressive Disorder |
| D019964 | Mood Disorders |
| D001523 | Mental Disorders |
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| Original Energy Light prototype | Device | 9000 lux 20 minutes in the morning |
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| Original Energy Light prototype | Device | 9000 lux 30 minutes in the morning |
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