Luteal Support and Intrauterine Insemination (IUI) With Clomiphene Citrate

Ovulation Induction With Clomiphene Citrate: to Support or Not to Support the Luteal Phase

The purpose of this study is to assess the effect of luteal phase supplement (LPS) on pregnancy rate in IUI cycles stimulated with clomiphene citrate.

Inclusion Criteria:

• Age ≤ 36 years
• Body mass index between 18 and 29
• Presence of both ovaries
• Basal levels of estradiol (≤ 80 pg/ml) and progesterone (≤ 1.6ng/ml) on day one of the cycle and a day three FSH level of <12IU/L
• Patients can enter the study only once.
• Only the first IUI attempt will be included ( at the 2nd and 3 rd attempt progesterone could be administrated if it is necessary but these attempts will be excluded from the study)
• Normal HSG (maximum 3 months prior starting the stimulation).
• Donor sperm can be included

Exclusion Criteria:

• Polycystic ovarian syndrome (Rotterdam criteria)
• Endometriosis(≥AFS III)