The purpose of this study was to prospectively evaluate the effect of cancer pain management protocol on hospitalized cancer patients.

Inclusion Criteria:

• Hospitalized patient with the somatic and/or visceral pain having an untreated intensity greater than 3 on a 10 cm visual analog scale (VAS; 0 = no pain, 10 = unbearable pain)over the week prior to enrollment
• A minimum age of 18 years

Exclusion Criteria:

• Opioid intolerance
• No longer treatment for their underlying disease.
• Intracerebral primary or metastatic lesion
• Impaired sensory or cognitive function
• Pregnant or lactating woman
• Women of child bearing potential not using a contraceptive method
• Sexually active fertile men not using effective birth control during medication of study drug and up to 6 months after completion of study drug if their partners are women of child-bearing potential
• Any patients judged by the investigator to be unfit to participate in the study