The Effects of Trancranial Magnetic Stimulation Multichannel Stimulator on Motor Excitation

The Effects of Trancranial Magnetic Stimulation Multichannel Stimulator on Motor Excitation

Our aim is to Test the influence of a new multichanel Transcranial Magnetic Stimulation stimulator (Multiway) on motor excitation, in comparision to a wildly used Magstim Super Rapid 2 single channel stimulator.

Each of the 20 Healthy subjects that are inticipated to inrole to the study wiil undergo 6 simple procedures which are designed to compare the motor threshold obtained by diffrent combination of TMs coils (figure 8, double cone coil,H coil array) and stimulators (Multiway, Super Rapid 2).

The entire length of the procedures is about 4 hours and all subjects will be paid for their participation in the study.

Our main hypothesis is that the motor threshold obtained by the multichanel stimulator will be significtly lower then the single chanel stimulator.

Inclusion Criteria:

1. Individuals between the ages of 18-65
2. Right handed individuals
3. Individual provides Negative responses to the questions on the safety questionnaire completed prior to TMS treatment.
4. Individual gave both written and verbal consent to participation in the study.

Exclusion Criteria:

1. Individual suffers from an Axis I disorder, as diagnosed in a Clinical interview with a Psychiatrist.
2. Individual suffers from an Axis II disorder, as diagnosed in a Clinical interview with a Psychiatrist.
3. Individual has a history of high blood pressure.
4. Individual has a history of epilepsy, epileptic seizure, or febrile seizures.
5. Individual has family members with a history of epilepsy, epileptic seizures or febrile seizures.
6. Individual has a history of head injury.
7. Individual has any metal implants in head (except for dental implants)
8. Individual has history of surgery, including metal implants or individual has a known history of metal particals in the eye, heart pumps, neurostimulator use, or any other medical pump.
9. Individual has a history of migrane.
10. Individual has a history of hearing problems or deafness.
11. Individual has a hisotry of hearing aids or implants.
12. Individual has a hisotry of drug or alcohol addiction.
13. Individual is pregnant or is sexually active and not using contraception.
14. Individual is to difficult to contact.
15. Indicidual has a legal gaurdian.
16. Individual is currently enroleld in another medical study.
17. Individual is a soldier, a prisoner or a convict.