BIIB014 Cardiovascular Monitoring Study

A Single-Center, Randomized, Placebo-Controlled, Double-Blind, Crossover Study to Evaluate the Cardiovascular Effects of Single Doses of Oral BIIB014 in Healthy Volunteers

The study will examine the effects of a single dose of BIIB014 on blood pressure and haemodynamic variables in healthy volunteers over 24 hours.

Inclusion Criteria:

• Healthy male or female subjects
• Between the ages of 18 and 50, inclusive.
• Must have a body mass index (BMI) between 19 kg/m2 and 30 kg/m2, inclusive

Exclusion Criteria:

• Clinically significant abnormalities (as determined by the Investigator)
• Other unspecified reason that would make the subject unsuitable for enrollment (as determined by the Investigator)